SCHEMBL12698778

SCHEMBL12698778

C=C1Oc2ccc(Cl)cc2N1CC

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 4/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTT P42858 2/20 0.39
USP2 O75604 1/20 0.39
AHR P35869 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 4/20 0.37
TSHR P16473 2/20 0.37
KMO O15229 1/20 0.36
THRB P10828 3/20 0.36
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12690998 0.76 SLC1A3 (0.36) PIM1MEN1KMT2ATDP1HTT
SCHEMBL10069652 0.75 P2RX4 (0.40) PIM1MEN1KMT2ATDP1HTT
SCHEMBL13712698 0.73 MAPT (0.41) MEN1KMT2AMAPTALDH1A1
SCHEMBL12203796 0.70 USP2 (0.67) MEN1KMT2AALOX15HSD17B10HTT
SCHEMBL24022881 0.69 ALOX15 (0.54) MEN1KMT2AALOX15HSD17B10HTT
SCHEMBL10131268 0.68 ALDH1A1 (0.34) MEN1KMT2ATDP1ALOX15HSD17B10
SCHEMBL10137943 0.67 MEN1 (0.38) PIM1MEN1KMT2ATDP1ALOX15
SCHEMBL13709031 0.67 KMT2A (0.41) PIM1MEN1KMT2ATDP1ALOX15
SCHEMBL13393380 0.66 PIM1 (0.59) PIM1MEN1KMT2ATDP1USP2
SCHEMBL6106184 0.64 MEN1 (0.93) PIM1MEN1KMT2ATDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2503389-A2 Non-resonant two-photon absorbing material, non-resonant two-photon emitting material, and method for inducing absorption or generating emission of non-resonant two photon by using the material. FUJIFILM Corporation (JP) 2012-09-26 EP disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-7771915-B2 Two-photon absorbing optical recording material and two-photon absorbing optical recording and reproducing method FUJIFILM CORPORATION (JP) 2010-08-10 US disclosed
US-7582391-B2 Two-photon absorption decolorizable material, two-photon absorption refractive index modulation material, two-photon absorption polymerization material, two-photon absorption polymerization method and three-dimensional optical recording material FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7582391-B2 Two-photon absorption decolorizable material, two-photon absorption refractive index modulation material, two-photon absorption polymerization material, two-photon absorption polymerization method and three-dimensional optical recording material FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed