SCHEMBL1269989

SCHEMBL1269989

O=Cc1ccc(O)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
MTOR P42345 1/20 0.47
ERN1 O75460 4/20 0.47
SIRT1 Q96EB6 1/20 0.44
TYR P14679 2/20 0.42
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
ESRRB O95718 1/20 0.42
ESRRA P11474 1/20 0.42
ALDH5A1 P51649 1/20 0.41
ABAT P80404 1/20 0.41
PRKDC P78527 1/20 0.41
TTR P02766 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
ENPP2 Q13822 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289452 0.82 BACE1 (0.49) NPC1MTORERN1TYRTRIM24
SCHEMBL31302309 0.82 BACE1 (0.49) NPC1MTORERN1TYRTRIM24
SCHEMBL7913737 0.78 TRIM24 (0.47) ERN1TYRTRIM24TRIM33ESR1
SCHEMBL29952866 0.78 TRIM24 (0.47) ERN1TYRTRIM24TRIM33ESR1
SCHEMBL5172746 0.77 NPC1 (0.47) NPC1MTORSIRT1TYRESR1
SCHEMBL93513 0.76 TYR (0.61) TYRTRIM24TRIM33PRKDCTTR
SCHEMBL27645627 0.76 TYR (0.61) TYRTRIM24TRIM33PRKDCTTR
SCHEMBL1162125 0.76 ERN1 (0.56) ERN1TRIM24TRIM33PRKDCALDH1A1
SCHEMBL30335110 0.76 TYR (0.61) TYRTRIM24TRIM33PRKDCTTR
Hydrochloric Acid SCHEMBL8726620 0.74 TYR (0.59) TYRTRIM24TRIM33PRKDCTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536509-B Synthesis method of 2-bromo-4-hydroxybenzaldehyde 苏州当量生物医药有限公司 2023-11-07 CN claimed
CN-114621290-B Phosphorus-carbole compound with different spatial structures, and preparation method and application thereof 华南理工大学 2023-08-22 CN claimed
CN-115536509-A Synthesis method of 2-bromo-4-hydroxybenzaldehyde 苏州金蚕新材料科技有限公司 2022-12-30 CN claimed
CN-114621290-A Phosphocorrole compounds with different spatial structures and preparation method and application thereof 华南理工大学 2022-06-14 CN claimed
CN-110183328-A One kind diene monomers containing carboxylate structure and its polyester and sulfur-bearing polyester 贵州大学 2019-08-30 CN claimed
CN-106565442-B The preparation method of 3- (3- luorobenzyl) -4- (3- fluorine benzyloxy) benzaldehyde 浙江美诺华药物化学有限公司 2019-07-16 CN claimed
CN-106632223-B 2- (the bromo- 4- of 3- (3- fluorine benzyloxy) phenyl) -1,3- dioxolanes and preparation method thereof 浙江美诺华药物化学有限公司 2019-04-23 CN claimed
CN-106188011-B The ultrasound synthesis and application of quaternary ring-type beta-lactam derivatives based on arylpyrazole skeleton 中南民族大学 2018-06-29 CN claimed
CN-107954844-A A kind of method with parahydroxyben-zaldehyde synthesis of vanillin 昆山亚香香料股份有限公司 2018-04-24 CN claimed
CN-107382686-A A kind of circulation preparation method of the hydroxy benzaldehyde of 3 bromine 4 毕佳 2017-11-24 CN claimed
CN-101531702-B Super-sweet dipeptide compound containing halogen and preparation method and application thereof SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2011-12-21 CN claimed
CN-101250097-B Method for preparing 3,5-dibromine-4-hydroxy benzaldehyde SHANDONG MORIS CHEMICAL CO LTD 2011-05-11 CN claimed
CN-101240166-B Bromobenzothiazoles luminous agent and preparation method thereof UNIV JIANGNAN 2010-09-29 CN claimed
CN-101250097-A Method for preparing 3,5-dibromine-4-hydroxy benzaldehyde SHANDONG MORIS CHEMICAL CO LTD (CN) 2008-08-27 CN claimed
CN-101240166-A Bromobenzothiazoles luminous agent and preparation method thereof UNIV JIANGNAN (CN) 2008-08-13 CN claimed
EP-1796627-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-06-20 EP claimed
WO-2007019931-A1 AGENT FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-02-22 WO claimed
WO-2006040015-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-04-20 WO claimed
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
EP-0423010-B1 METHOD FOR THE PRODUCTION OF ALKOXYBENZALDEHYDES RHONE-POULENC CHIMIE (FR) 1993-09-29 EP claimed