Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 7/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31302309 | 1.00 | BACE1 (0.49) | BACE1ERN1ALDH5A1ABATPRKDC | |
| SCHEMBL1269989 | 0.82 | NPC1 (0.47) | ERN1ALDH5A1ABATPRKDCKDM4E | |
| SCHEMBL2480246 | 0.80 | XDH (0.43) | BACE1ERN1POLBMAPTTDP1 | |
| SCHEMBL29265103 | 0.79 | BACE1 (0.51) | BACE1L3MBTL1KDM4EALDH1A1EGFR | |
| SCHEMBL7913737 | 0.78 | TRIM24 (0.47) | ERN1ALDH5A1ABATL3MBTL1KDM4E | |
| SCHEMBL29952866 | 0.78 | TRIM24 (0.47) | ERN1ALDH5A1ABATL3MBTL1KDM4E | |
| SCHEMBL2104286 | 0.77 | BACE1 (0.45) | BACE1L3MBTL1NPC1MEN1RAB9A | |
| SCHEMBL29265089 | 0.77 | BACE1 (0.45) | BACE1L3MBTL1KDM4EALDH1A1EGFR | |
| SCHEMBL414267 | 0.76 | ERN1 (0.61) | ERN1PRKDCALDH1A1TDP1MEN1 | |
| SCHEMBL36835 | 0.76 | ERN1 (0.61) | ERN1L3MBTL1KDM4EALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 824 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925626-B | Novel aporphine compound and preparation method and application thereof | 中国药科大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119841800-A | Method for preparing urolithin A by one-pot method | 天津大学浙江研究院(绍兴) | 2025-04-18 | — | — | CN | claimed |
| CN-119564591-A | Keli-boria ointment and its production process | 江苏晨牌邦德药业有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119390742-A | Hydroxy-exposed urolithin A-8-O galactose glycoside and its synthesis process and application | 江西师范大学 | 2025-02-07 | — | — | CN | claimed |
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2025-01-14 | — | — | US | claimed |
| CN-117024332-A | Near-infrared singlet oxygen luminescent probe with high signal-to-noise ratio and high stability and preparation method and application thereof | 华东理工大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116239608-A | Near-infrared two-region organic small molecule chemiluminescent probe and preparation and application thereof | 福州市微纳新创医疗科技有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-115925626-A | Novel aporphine compound and preparation method and application thereof | 中国药科大学 | 2023-04-07 | — | — | CN | claimed |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | GUANGDONG OXO CHEM LTD. (CN) | 2022-08-04 | — | — | US | claimed |
| CN-112851703-A | Preparation method of clitorium | 合肥立方制药股份有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-110804009-A | Chemiluminescent substrate with high chemiluminescent intensity, long wavelength and good stability, and preparation method and application thereof | 华东理工大学 | 2020-02-18 | — | — | CN | claimed |
| WO-2018216032-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2018-11-29 | — | — | WO | claimed |
| CN-108864160-A | The preparation method of boron-containing small molecules | 苏州旺山旺水生物医药有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108530476-A | A kind of preparation method of gram of vertical boron sieve intermediate | 武汉轻工大学 | 2018-09-14 | — | — | CN | claimed |
| WO-2018115362-A1 | PROCESS FOR PREPARING 4-[(1-HYDROXY-1,3-DIHYDRO-2,1-BENZOXABOROL-5-YL)OXY]BENZONITRILE (CRISABOROLE) | LABORATORIOS LESVI, SL (ES) | 2018-06-28 | — | — | WO | claimed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-102911157-B | (E)-3-[2-bromo-5-(3-substituted propoxy)]phenyl-N-{4-methyl-3-[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl acrylamide compound | UNIV SHENYANG PHARMACEUTICAL | 2014-04-02 | — | — | CN | claimed |
| CN-102911157-A | (E)-3-[2-bromo-5-(3-substituted propoxy)]phenyl-N-{4-methyl-3-[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl acrylamide compound | UNIV SHENYANG PHARMACEUTICAL | 2013-02-06 | — | — | CN | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| WO-2005037756-A2 | NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-04-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | SOST, BPGM, PFKFB3 | BACE1 4577/4885ERN1 4071/4885ALDH5A1 447/4885 |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | SOST, BPGM, PFKFB3 | BACE1 4577/4885ERN1 4071/4885ALDH5A1 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.