Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.69 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.69 |
| ▸ | AHCY | P23526 | 6/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001403 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL22354944 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL15870254 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL20580185 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL26752544 | 0.91 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL22354823 | 0.91 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL22332144 | 0.89 | ADORA3 (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL20925712 | 0.89 | ADORA3 (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL20925696 | 0.89 | ADORA3 (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13400312 | 0.88 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090136-A1 | NOVEL ANTIBACTERIAL COMPOUNDS | INSTITUT PASTEUR (FR) | 2012-07-05 | — | — | WO | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |