Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.69 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.69 |
| ▸ | AHCY | P23526 | 6/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22354944 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL15870254 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL12700167 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL20580185 | 1.00 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL26752544 | 0.91 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL22354823 | 0.91 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL22332144 | 0.89 | ADORA3 (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL20925712 | 0.89 | ADORA3 (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL20925696 | 0.89 | ADORA3 (0.69) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13400312 | 0.88 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12209090-B2 | 3,6-disubstituted-2-pyridinaldoxime scaffolds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-01-28 | — | — | US | disclosed |
| EP-4384519-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | Albert-Ludwigs-Universität Freiburg (DE) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |
| US-20220081442-A1 | 3,6-DISUBSTITUTED-2-PYRIDINALDOXIME SCAFFOLDS | UNIVERSITÉ DE STRASBOURG (FR) | 2022-03-17 | — | — | US | disclosed |
| EP-3696170-A1 | 3,6-DISUBSTITUTED-2-PYRIDINALDOXIME SCAFFOLDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-08-19 | — | — | EP | disclosed |
| US-10428104-B2 | Substituted nucleoside derivatives useful as anticancer agents | PFIZER INC. (US) | 2019-10-01 | — | — | US | disclosed |
| US-10077284-B2 | UBA5 inhibitors | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2018-09-18 | — | — | US | disclosed |
| US-20170107247-A1 | UBA5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-04-20 | — | — | US | disclosed |
| US-20170107247-A1 | UBA5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-04-20 | — | — | US | disclosed |
| US-20170107247-A1 | UBA5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-04-20 | — | — | US | disclosed |
| WO-2015179955-A1 | UBA5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-12-03 | — | — | WO | disclosed |
| WO-2015179955-A1 | UBA5 INHIBITORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-12-03 | — | — | WO | disclosed |
| US-8158376-B2 | Bisubstrate fluorescent probe binding to protein kinases | UNIVERSITY OF TARTU (EE) | 2012-04-17 | — | — | US | disclosed |
| US-8158376-B2 | Bisubstrate fluorescent probe binding to protein kinases | UNIVERSITY OF TARTU (EE) | 2012-04-17 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | CREDIT SUISSE AG | 2009-09-17 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511133-B2 | Adenosine A3 receptor agonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2009-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233878-A1 | NOVEL ADENOSINE A3 RECEPTOR AGONISTS | ADORA3, ADORA1, ADORA2A | PI4KA 1207/4885PI4K2B 2155/4885PI4K2A 1681/4885 |
| US-10428104-B2 | Substituted nucleoside derivatives useful as anticancer agents | TYMP, NME1, DPYD | PI4KA 769/4885PI4K2B 1095/4885PI4K2A 903/4885 |
| US-10077284-B2 | UBA5 inhibitors | UBQLN2, UBTF, UBQLN1 | PI4KA 1575/4885PI4K2B 1568/4885PI4K2A 2218/4885 |
| US-12209090-B2 | 3,6-disubstituted-2-pyridinaldoxime scaffolds | XDH, TPX2, CYP4X1 | PI4KA 2999/4885PI4K2B 2361/4885PI4K2A 2567/4885 |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | ADK, PRKCH, DMPK | PI4KA 265/4885PI4K2B 389/4885PI4K2A 388/4885 |
| US-20170107247-A1 | UBA5 INHIBITORS | UBQLN2, UBTF, UBQLN1 | PI4KA 1575/4885PI4K2B 1568/4885PI4K2A 2218/4885 |
| US-20220081442-A1 | 3,6-DISUBSTITUTED-2-PYRIDINALDOXIME SCAFFOLDS | XDH, TPX2, CYP4X1 | PI4KA 2999/4885PI4K2B 2361/4885PI4K2A 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.