SCHEMBL1270076

SCHEMBL1270076

Nc1ccc(-c2ccccc2Sc2ccccc2-c2ccc(N)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
HSD17B10 Q99714 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
ALDH1A1 P00352 3/20 0.43
TP53 P04637 2/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
OPRK1 P41145 1/20 0.42
NCOA1 Q15788 2/20 0.41
NCOA3 Q9Y6Q9 2/20 0.41
ALOX5AP P20292 3/20 0.40
FEN1 P39748 3/20 0.40
PRKCZ Q05513 1/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3787013 0.88 CYP3A4 (0.46) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL2785165 0.83 ALOX5AP (0.46) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL27993955 0.81 CYP3A4 (0.43) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL1782448 0.80 HTR7 (0.50) HSD17B10TDP1ALDH1A1MAPTKDM4E
SCHEMBL9246341 0.80 HSD17B10 (0.63) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL6282287 0.78 ALOX5AP (0.50) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL3789854 0.78 HTR7 (0.46) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL25127003 0.78 DRD1 (0.55) CYP3A4ALDH1A1MEN1KMT2AMAPT
SCHEMBL30208583 0.78 HSD17B10 (0.68) CYP3A4HSD17B10TDP1TAAR1ALDH1A1
SCHEMBL29118206 0.78 HSD17B10 (0.68) CYP3A4HSD17B10TDP1TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113677755-A Substrate for heat-resistant electronic device 株式会社LG化学 2021-11-19 CN disclosed
CN-108291027-B Modified polyimide and curable resin composition 株式会社LG化学 2021-01-22 CN disclosed
EP-3562863-A1 METHODS OF MANUFACTURE FOR POLYETHERIMIDE SABIC Global Technologies B.V. (NL) 2019-11-06 EP disclosed
WO-2018126004-A1 METHODS OF MANUFACTURE FOR POLYETHERIMIDE SABIC GLOBAL TECHNOLOGIES B. V. (NL) 2018-07-05 WO disclosed
CN-103122140-B Resin composition and molded article comprising the same UNITIKA LTD 2015-07-22 CN disclosed
CN-103270070-B RESIN COMPOSITION, CURED OBJECT, RESIN FILM, AND WIRING BOARD ASAHI KASEI E MATERIALS CORP 2015-02-18 CN disclosed
WO-2011016094-A1 HEAT RESISTANT RESIN, COMPOSITION THEREOF, RESIN/METAL LAMINATE AND CIRCUIT BOARD MITSUI CHEMICALS, INC. (JP) 2011-02-10 WO disclosed
US-20080129182-A1 VACUUM ENVELOPE FOR IMAGE DISPLAY DEVICE AND SEALANT FOR IMAGE DISPLAY DEVICE ASAHI GLASS COMPANY LIMITED (JP) 2008-06-05 US disclosed
US-20070141279-A1 ENVELOPE FOR IMAGE DISPLAY DEVICE, HERMETIC SEALING MATERIAL, SEALING METHOD AND IMAGE DISPLAY DEVICE ASAHI GLASS CO., LTD. (JP) 2007-06-21 US disclosed
EP-1783806-A1 ENVELOPE FOR IMAGE DISPLAY, SEALING MATERIAL, SEALING METHOD, AND IMAGE DISPLAY Asahi Glass Company, Limited (JP) 2007-05-09 EP disclosed
US-20040082754-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2004-04-29 US disclosed
US-20030158370-A1 Process for producing polyimide MITSUI CHEMICALS, INC. (JP) 2003-08-21 US disclosed
US-20030092870-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed
EP-1273611-A1 PROCESS FOR PRODUCING POLYIMIDE Mitsui Chemicals, Inc. (JP) 2003-01-08 EP disclosed
US-6458912-B1 1,3-BIS(4-AMINOPHENOXY)BENZENE REPRESENTED BY THE CHEMICAL FORMULA (3) FOR PRODUCTION OF THE ABOVE POLYIMIDE, CHARACTERIZED IN THAT THE CONTENT OF AN AZO COMPOUND IS FROM 0.0 TO 0.2%. THE THERMOPLASTIC POLYIMIDE OF THE PRESENT MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
EP-1090945-A1 CRYSTALLINE POLYIMIDE FOR MELT MOLDING WITH SATISFACTORY THERMAL STABILITY Mitsui Chemicals, Inc. (JP) 2001-04-11 EP disclosed
EP-0591551-B1 POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1998-03-04 EP disclosed
US-5580918-A MOLDING BLEND OF POLYIMIDE BASED ON A TETRACARBOXYLIC ACID AND A P,P'-BIS(3-AMINOPHENOXY)DIPHENYL ETHER AND A POLYETHER KETONE COPOLYMER; DIMENSIONAL STABILITY; ANTIPEELING AGENTS; FLOWABILITY; ANISTROPIC MITSUI TOATSU CHEMICALS, INC. (JP) 1996-12-03 US disclosed
EP-0591551-A1 POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092870-A1 Novel aromatic diamine and polyimide thereof DDT, AOC1, H1-4 CYP3A4 857/4885HSD17B10 3784/4885TDP1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.