SCHEMBL12701802

SCHEMBL12701802

C=C(C)C(=O)OCCCCCCCCCCC[Si](C)(C)O

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 1/20 0.34
ACHE P22303 6/20 0.33
NAAA Q02083 1/20 0.32
RAD52 P43351 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13343088 0.98 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL932961 0.93 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
Lithium SCHEMBL8074773 0.91 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1
SCHEMBL12701990 0.90 THRB (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL12701962 0.90 THRB (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL30468107 0.89 TSHR (0.53) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27527876 0.85 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16070946 0.85 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL25329219 0.85 THRB (0.52) TSHRPOLBAPEX1HTTTDP1
SCHEMBL22554427 0.84 TSHR (0.83) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9018332-B2 Polyorganosiloxane containing methacryloxy group or acryloxy group and method for producing the same DOW CORNING TORAY COMPANY, LTD. (JP) 2015-04-28 US disclosed
US-20110092660-A1 Polyorganosiloxane Containing Methacryloxy Group Or Acryloxy Group And Method For Producing The Same DOW CORNING TORAY COMPANY, LTD. (JP) 2011-04-21 US disclosed