Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932961 | 0.98 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL30468107 | 0.95 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13343088 | 0.93 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12701802 | 0.91 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15081586 | 0.88 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL744453 | 0.87 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25329219 | 0.86 | THRB (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12095074 | 0.86 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15115406 | 0.86 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL98210 | 0.85 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156437-A | Curable compositions using siloxane grafted vinyl polymers | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |