SCHEMBL1270207

SCHEMBL1270207

C=CC(OCC1CO1)c1ccccc1.C=Cc1ccccc1C=C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.35
GLA P06280 1/20 0.35
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CASR P41180 1/20 0.33
MGLL Q99685 3/20 0.33
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
FGFR1 P11362 1/20 0.31
SRC P12931 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194266 0.93 TDP1 (0.46) TDP1ALDH1A1GLATP53CYP3A4
SCHEMBL4776489 0.89 TDP1 (0.35) TDP1ALDH1A1GLA
Chlorobenzene SCHEMBL1194559 0.86 TDP1 (0.41) TDP1ALDH1A1GLATP53CYP3A4
SCHEMBL6525597 0.78 HPGD (0.43) ALDH1A1CYP3A4MGLL
SCHEMBL17761547 0.77 ALDH1A1 (0.50) TDP1ALDH1A1GLATP53CYP3A4
SCHEMBL23855002 0.75 TDP1 (0.40) TDP1ALDH1A1GLATP53CYP3A4
SCHEMBL29393285 0.75 TDP1 (0.44) TDP1ALDH1A1GLATP53CYP3A4
SCHEMBL28866610 0.75 MGLL (0.33) TDP1ALDH1A1CASRMGLL
SCHEMBL2059110 0.73 ALDH1A1 (0.39) TDP1ALDH1A1GLATP53CYP3A4
SCHEMBL20526226 0.72 TDP1 (0.44) TDP1ALDH1A1GLATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520216-B Multimodal chromatography media for protein separations 戴安公司 2022-09-06 CN disclosed
EP-3570974-B1 MULTIMODAL CHROMATOGRAPHIC MEDIA FOR PROTEIN SEPARATION DIONEX CORP (US) 2021-03-31 EP disclosed
CN-110520216-A Multimodal chromatography media for protein separations DIONEX CORP 2019-11-29 CN disclosed
EP-2279034-B1 FUNCTIONALIZED SUBSTRATES WITH ION-EXCHANGE PROPERTIES DIONEX CORP (US) 2019-05-22 EP disclosed
WO-2018136666-A1 MULTIMODAL CHROMATOGRAPHIC MEDIA FOR PROTEIN SEPARATION DIONEX CORPORATION (US) 2018-07-26 WO disclosed
US-9314712-B2 Functionalized substrates with ion-exchange properties DIONEX CORPORATION (US) 2016-04-19 US disclosed
US-9310344-B2 HILIC/anion-exchange/cation-exchange multimodal media DIONEX CORPORATION (US) 2016-04-12 US disclosed
EP-2745904-B1 HILIC/Anion-Exchange/Cation-Exchange Multimodal Media DIONEX CORP (US) 2015-12-16 EP disclosed
US-20140370614-A1 HILIC / ANION-EXCHANGE / CATION-EXCHANGE MULTIMODAL MEDIA DIONEX CORPORATION 2014-12-18 US disclosed
EP-2745904-A1 HILIC/Anion-Exchange/Cation-Exchange Multimodal Media Dionex Corporation (US) 2014-06-25 EP disclosed
EP-2279034-A1 FUNCTIONALIZED SUBSTRATES WITH ION-EXCHANGE PROPERTIES DIONEX CORPORATION (US) 2011-02-02 EP disclosed
WO-2009137275-A1 FUNCTIONALIZED SUBSTRATES WITH ION-EXCHANGE PROPERTIES DIONEX CORPORATION (US) 2009-11-12 WO disclosed
US-20090277838-A1 Functionalized substrates with ion-exchange properties DIONEX CORPORATION (US) 2009-11-12 US disclosed