Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.76 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | GMNN | O75496 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | THPO | P40225 | 1/20 | 0.76 |
| ▸ | MTOR | P42345 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | CETP | P11597 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | UBE2N | P61088 | 1/20 | 0.76 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118653 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859677 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859681 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859678 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6118549 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859679 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6117945 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6118606 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859683 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16104483 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183721-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-07-02 | — | — | US | claimed |
| US-20150183721-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-07-02 | — | — | US | disclosed |
| EP-2462105-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2012-06-13 | — | — | EP | disclosed |
| US-20120129947-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-05-24 | — | — | US | disclosed |
| WO-2011016033-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183721-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | AADAT, ABAT, ADH1A | CYP2D6 2934/4885SPHK1 968/4885LMNA 1193/4885 |
| US-20120129947-A1 | AMINO-ALCOHOL ANALOGUES AND USES THEREOF | AADAT, ABAT, ADH1A | CYP2D6 2934/4885SPHK1 968/4885LMNA 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.