Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891651 | 0.87 | LTB4R (0.41) | PPARGLTB4RPTGESALOX5PPARD | |
| SCHEMBL9891650 | 0.86 | PPARG (0.42) | PPARGLTB4RPTGESALOX5PPARD | |
| SCHEMBL9889103 | 0.70 | PTGER1 (0.50) | AKR1C3HTTMAPTMTNR1AMTNR1B | |
| SCHEMBL18292873 | 0.70 | MAPT (0.48) | PPARAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL8036310 | 0.70 | MTNR1A (0.40) | MTNR1AMTNR1B | |
| SCHEMBL9889129 | 0.70 | PTGER1 (0.49) | ITGB1ITGA4AKR1C3MTNR1AMTNR1B | |
| SCHEMBL2542877 | 0.69 | LTB4R (0.62) | PPARGLTB4RPPARAHTTMAPT | |
| SCHEMBL16306929 | 0.68 | SMN1; SMN2 (0.51) | PPARGLTB4RPPARDPPARAHTT | |
| SCHEMBL7198061 | 0.68 | LTB4R (0.47) | PPARGLTB4RPTGESALOX5HTT | |
| SCHEMBL19792614 | 0.68 | FFAR4 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311939-A1 | Polypeptide immobilization | The University of Chicago (US) | 2011-04-20 | — | — | EP | disclosed |