SCHEMBL127044

SCHEMBL127044

C#CC(C)(O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.43
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
KMT2A Q03164 2/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C19 P33261 3/20 0.39
HIF1A Q16665 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28606840 1.00 ALDH1A1 (0.43) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL26105458 1.00 ALDH1A1 (0.43) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL28956828 0.88 ALDH1A1 (0.35) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL17210661 0.87 MEN1 (0.39) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL11482162 0.87 CYP2C9 (0.47) ALDH1A1ESR1ESR2CYP3A4MAPT
Meparfynol SCHEMBL29145003 0.87 CYP2C19 (0.35) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL11486699 0.82 LTA4H (0.44) ALDH1A1MAPK1KMT2ATSHRMAPT
SCHEMBL6017366 0.80 ALDH1A1 (0.46) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL15763664 0.79 TSHR (0.48) ALDH1A1ESR1CYP3A4KMT2ATSHR
SCHEMBL4271577 0.77 KMT2A (0.58) CYP3A4MAPK1KMT2ATSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3897 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122034344-A Preparation method of composite silicon rubber gasket and composite silicon rubber gasket 东莞市兆科电子材料科技有限公司 2026-05-15 CN claimed
WO-2025123334-A1 TWO-PART SILICONE COMPOSITION AND FOAM SEALANT AND ASSEMBLY MADE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-06-19 WO claimed
CN-120137589-A Single-component organic silicon adhesive for chip packaging and preparation method thereof 万华化学集团股份有限公司 2025-06-13 CN claimed
CN-120118661-A Thermal interface material, preparation method and application 深圳先进电子材料国际创新研究院 2025-06-10 CN claimed
CN-119955312-A Low-viscosity high-performance anti-sedimentation conductive silicon rubber and preparation method thereof 硅宝正基(深圳)科技有限公司 2025-05-09 CN claimed
CN-119912902-A Double-component organic silicon heat conduction pouring sealant with excellent flexibility and preparation method thereof 哈尔滨工业大学 2025-05-02 CN claimed
CN-119875576-A Bearing material for Micro LED laser mass transfer and preparation method and application thereof 深圳市化讯半导体材料有限公司 2025-04-25 CN claimed
CN-119640591-B Mosquito-repellent and insect-repellent coating finishing agent and application thereof to outdoor tent fabric 江苏恒力化纤股份有限公司 2025-04-22 CN claimed
CN-119242263-B Low-density heat-conducting pouring sealant and preparation method and application thereof 广州信粤新材料科技有限公司 2025-04-15 CN claimed
CN-119799010-A Organic silicon heat-conducting gel, preparation method thereof, heat-conducting material and application 深圳先进电子材料国际创新研究院 2025-04-11 CN claimed
US-5914192-A COMPOSITION COMPRISING POLYSILOXANES HAVING ALKENYL GROUPS AND SILICON-BONDED HYDROGEN ATOMS, ALCOHOL CONTAINING TRIPLE BOND, COMPOUND HAVING TRIPLE BOND-CONTAINING HYDROCARBON GROUPS BONDED TO SILICON THROUGH OXYGEN ATOM, PLATINUM CATALYST DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-06-22 US claimed
US-5904887-A Molding method of composite DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-05-18 US claimed
EP-0845510-A2 Silicone release coating compositions Dow Corning Toray Silicone Company, Ltd. (JP) 1998-06-03 EP claimed
US-5708046-A ALKENYL SILOXANES, ORGANOHYDROGENSILOXANES, POLYMERIZATION INHIBITORS FOR STORAGE STABILITY DOW CORNING CORPORATION (US) 1998-01-13 US claimed
EP-0764703-A2 Silicone release coating compositions Dow Corning Toray Silicone Company Ltd. (JP) 1997-03-26 EP claimed
EP-0704492-A2 Molding method of composite Dow Corning Toray Silicone Company, Limited (JP) 1996-04-03 EP claimed
US-5334687-A Hydrosilating blend of polysiloxanes, a platinum catalyst and curing inhibitors comprising acyclic diamines or a primary amine and an acetylenic alcohol; shelf life SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-08-02 US claimed
US-5214074-A Unsaturated compound for controlling curing reaction such that it takes place at the same rate as decomposition of foaming agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-05-25 US claimed
US-4356325-A Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-10-26 US claimed
US-4100208-A Process for the production of unsaturated compounds SNAM PROGETTI S.P.A. (IT) 1978-07-11 US claimed