SCHEMBL1270445

SCHEMBL1270445

C=C(CCC(CCCC)OCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
BACE1 P56817 1/20 0.36
CA2 P00918 5/20 0.35
MAPK1 P28482 2/20 0.35
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CA1 P00915 2/20 0.33
THRB P10828 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
FFAR1 O14842 2/20 0.32
FFAR4 Q5NUL3 1/20 0.32
AKR1B1 P15121 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632367 0.90 CHRM1 (0.33) TDP1
SCHEMBL17709704 0.89 ACHE (0.35) ACHEBACE1CA2MAPK1TSHR
SCHEMBL10704325 0.85 TET2 (0.37) ACHEBACE1CA2MAPK1TSHR
SCHEMBL14151468 0.84 TET2 (0.31)
SCHEMBL11417018 0.82 AKR1B1 (0.45) ACHEBACE1TSHRTDP1FFAR1
SCHEMBL17709709 0.81
SCHEMBL262088 0.78 TSHR (0.32) CA2MAPK1TSHRATMTHRB
SCHEMBL17709707 0.78 LPAR1 (0.34) ACHEBACE1TSHRTHRBFNTA
SCHEMBL3748664 0.77 TET2 (0.38)
SCHEMBL486621 0.77 TET2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507632-B2 A polyesterurethane copolymer containing a polycaprolactone-modified alkyl(meth)acrylate; self-repairing coatings or paints; optical films NATOCO CO., LTD. (JP) 2013-08-13 US disclosed
US-7939608-B2 A polyesterurethane copolymer containing a polycaprolactone-modified alkyl(meth)acrylate; self-repairing coatings or paints; optical films NATOCO CO., LTD. (JP) 2011-05-10 US disclosed
US-7892284-B2 Intraocular lens and process for producing the same HOYA CORPORATION (JP) 2011-02-22 US disclosed
US-20080177384-A1 Intraocular Lens and Process for Producing the Same HOYA Medical Singapore Pte. Ltd. (SG) 2008-07-24 US disclosed
US-20080125550-A1 COMPOSITION CURABLE WITH ACTINIC ENERGY RAY AND USE THEREOF NATOCO CO., LTD. (JP) 2008-05-29 US disclosed
US-20070049653-A1 Composition Curable With Actinic Energy Ray and Use Thereof NATOCO CO., LTD. (JP) 2007-03-01 US disclosed
US-20070004817-A1 Composition Curable With Actinic Energy Ray and Use Thereof NATOCO CO., LTD. (JP) 2007-01-04 US disclosed
US-20050148739-A1 Composition curable with actinic energy ray and use thereof NATOCO CO., LTD. (JP) 2005-07-07 US disclosed