SCHEMBL3748664

SCHEMBL3748664

C=C(CCC(O)OCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.38
TET3 O43151 1/20 0.38
TET1 Q8NFU7 1/20 0.38
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486621 0.84 TET2 (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL828545 0.82 GABRP (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL27715501 0.81 GABRP (0.48) TET2TET3GRIK1GRIK2GRM1
SCHEMBL14151468 0.81 TET2 (0.31) TET2TET3TET1GRIK1GRIK2
SCHEMBL2843845 0.81 GRIK1 (0.38) TET2TET3TET1GRIK1GRIK2
SCHEMBL475008 0.79 TET2 (0.31) TET2TET3TET1
SCHEMBL9632367 0.79 CHRM1 (0.33) TET2TET3TET1
SCHEMBL5008759 0.77 TET2 (0.35) TET2TET3TET1GRIK1GRIK2
SCHEMBL7171781 0.77 EPHX1 (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL1270445 0.77 ACHE (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3256850-B1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES INC (US) 2025-07-09 EP claimed
EP-1509172-B1 PHOTOABLATABLE CORNEA INLAYS BAUSCH & LOMB (US) 2013-09-04 EP claimed
US-20130112623-A1 COMPOSITE MATERIAL JACOBS UNIVERSITY BREMEN GGMBH (DE) 2013-05-09 US claimed
EP-1515705-B1 FLUOROSILOXANE MATRIX CONTROLLED DIFFUSION DRUG DELIVERY SYSTEM BAUSCH & LOMB (US) 2006-06-21 EP claimed
EP-1177227-B1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORP (US) 2003-10-01 EP claimed
EP-0080680-B1 REFERENCE ELECTRODE CATHETER Sentron v.o.f. (NL) 1988-03-30 EP claimed
US-10385202-B2 Thermoplastic polymer composition and shaped article composed of the same KURARAY CO., LTD. (JP) 2019-08-20 US disclosed
US-20130112623-A1 COMPOSITE MATERIAL JACOBS UNIVERSITY BREMEN GGMBH (DE) 2013-05-09 US disclosed
US-20100273012-A1 THERMOPLASTIC POLYMER COMPOSITION AND SHAPED ARTICLE COMPOSED OF THE SAME KURARAY CO., LTD. (JP) 2010-10-28 US disclosed
WO-1993021274-A1 MULTILAYER CORE-SHELL POLYMER COMPOSITIONS AS TOUGHENER FOR THERMOSETS AND THERMOPLASTICS THE B.F. GOODRICH COMPANY (US) 1993-10-28 WO disclosed