SCHEMBL1270517

SCHEMBL1270517

C=CCN([S])CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL84275 0.96 ALDH1A1 (0.31)
Fluoride SCHEMBL4907712 0.96 ALDH1A1 (0.31)
Fluoride SCHEMBL11497479 0.96
Fluoride SCHEMBL10706553 0.96 ALDH1A1 (0.31)
Fluoride SCHEMBL10706543 0.96 ALDH1A1 (0.31)
SCHEMBL9056715 0.69
SCHEMBL7828526 0.69 ALDH1A1 (0.32)
SCHEMBL11070461 0.67 ALDH1A1 (0.35)
SCHEMBL20656 0.67 TSHR (0.43)
SCHEMBL7177724 0.67 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO claimed
EP-2057111-A1 A LARGE SCALE METHOD FOR THE DEOXOFLUORINATION OF KETONES Bayer Schering Pharma Aktiengesellschaft (DE) 2009-05-13 EP claimed
WO-2008022791-A1 A LARGE SCALE METHOD FOR THE DEOXOFLUORINATION OF KETONES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-02-28 WO claimed
EP-1318160-B1 Catalysts and process for the preparation of isocyanurate group containing polyisocyanates and their use DEGUSSA (DE) 2007-09-26 EP claimed
US-20030135007-A1 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2003-07-17 US claimed
EP-0907640-A1 SUBSTITUTED N-(4-PYRIDYL)-THIOAMIDES WITH PESTICIDE ACTIVITY BAYER AG (DE) 1999-04-14 EP claimed
WO-1997049683-A1 SUBSTITUTED N-(4-PYRIDYL)-THIOAMIDES WITH PESTICIDE ACTIVITY BAYER AKTIENGESELLSCHAFT (DE) 1997-12-31 WO claimed
EP-0181852-B1 SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS Monsanto Company (US) 1990-08-29 EP claimed
US-4655816-A PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1987-04-07 US claimed
EP-0181852-A1 Substituted 2,6-substituted pyridine compounds Monsanto Company (US) 1986-05-21 EP claimed
JP-10182598-A None JP disclosed
JP-4103596-A None JP disclosed
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO disclosed
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO disclosed
WO-2020037109-A1 PROCESSES FOR FLUORINATION DOW AGROSCIENCES LLC (US) 2020-02-20 WO disclosed
US-3976691-A Dialkylaminosulfur trifluorides as fluorinating agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-24 US disclosed
US-3976691-A Dialkylaminosulfur trifluorides as fluorinating agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-24 US disclosed
US-3976691-A Dialkylaminosulfur trifluorides as fluorinating agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-24 US disclosed
US-3914265-A FOR HYDROXY COMPOUNDS DU PONT 1975-10-21 US disclosed
US-3914265-A FOR HYDROXY COMPOUNDS DU PONT 1975-10-21 US disclosed