SCHEMBL11070461

SCHEMBL11070461

C=CCN(CC=C)N(CC=C)CC=C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7177724 1.00 ALDH1A1 (0.35) ALDH1A1TSHR
Hydrochloric Acid SCHEMBL7717766 0.96 ALDH1A1 (0.33) ALDH1A1TSHR
Bromide SCHEMBL29011443 0.92 ALDH1A1 (0.32) ALDH1A1
SCHEMBL2107571 0.83 MEN1 (0.36) ALDH1A1TSHR
SCHEMBL5187355 0.80 TSHR (0.32) TSHR
SCHEMBL1858709 0.78 PYCR1 (0.32)
SCHEMBL7568436 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL20656 0.73 TSHR (0.43) ALDH1A1TSHR
SCHEMBL7549527 0.73 TSHR (0.43) ALDH1A1TSHR
SCHEMBL2365396 0.72 ALDH1A1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4452797-A FOR CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1984-06-05 US disclosed
US-4332801-A HYPOTENSIVE; CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1982-06-01 US disclosed
US-4305939-A HYPOTENSIVE CASSELLA AG (DE) 1981-12-15 US disclosed