Sugi Predict

Sugi Predict / Compounds / SCHEMBL1270804

SCHEMBL1270804

SCHEMBL1270804

[c]1ccc(-c2cccc3c2ccc2ccccc23)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 3/20 0.54
▸ ALDH1A1 P00352 4/20 0.46
▸ HSD17B10 Q99714 3/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ CYP2A6 P11509 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ CA12 O43570 2/20 0.41
▸ CA1 P00915 2/20 0.41
▸ CA2 P00918 2/20 0.41
▸ CA9 Q16790 2/20 0.41
▸ PAX8 Q06710 1/20 0.41
▸ TNF P01375 1/20 0.41
▸ CYP1A2 P05177 3/20 0.40
▸ HIF1A Q16665 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ CYP1B1 Q16678 1/20 0.40
▸ HDAC8 Q9BY41 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2586304 1.00 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Water SCHEMBL27550628 0.90 CA12 (0.49) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL161269 0.90 CA12 (0.49) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL27297558 0.88 CA12 (0.47) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL27576521 0.88 CA12 (0.47) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL28787358 0.86 CA12 (0.46) ALDH1A1HSD17B10TDP1TSHRCA12
SCHEMBL668823 0.86 CA12 (0.54) CA12CA1CA2CA9TNF
SCHEMBL27620091 0.86 HPRT1 (0.67) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL2835699 0.86 HPRT1 (0.67) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL443518 0.84 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240147746-A1 ORGANIC COMPOUND AND USE THEREOF WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2024-05-02 — — US claimed
CN-116396292-A Organic compound and application thereof 武汉天马微电子有限公司 2023-07-07 — — CN claimed
CN-115710187-A Arylamine organic compound and organic electroluminescent device containing same 江苏三月科技股份有限公司 2023-02-24 — — CN claimed
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2020-06-16 — — US claimed
US-10566543-B2 Pyrimidine derivative and organic electroluminescent devices HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-18 — — US claimed
US-8968883-B2 Chrysene derivative materials E I DU PONT DE NEMOURS AND COMPANY (US) 2015-03-03 — — US claimed
US-8716699-B2 Organic light-emitting diodes having white light emission E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-06 — — US claimed
US-20130187140-A1 CHRYSENE DERIVATIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-25 — — US claimed
CN-102834483-A Chrysene derivative materials DU PONT 2012-12-19 — — CN claimed
EP-2494626-A2 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E. I. du Pont de Nemours and Company (US) 2012-09-05 — — EP claimed
EP-2464709-A1 CHRYSENE DERIVATIVE MATERIALS E. I. du Pont de Nemours and Company (US) 2012-06-20 — — EP claimed
WO-2011059807-A2 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-19 — — WO claimed
US-20110101316-A1 ORGANIC LIGHT-EMITTING DIODE LUMINAIRES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-05 — — US claimed
US-20110037381-A1 CHRYSENE DERIVATIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 — — US claimed
WO-2011019360-A1 CHRYSENE DERIVATIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 — — WO claimed
US-20100187981-A1 CHRYSENE DERIVATIVE HOST MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 — — US claimed
CN-118146204-A Amine compound, light-emitting element comprising amine compound, and display device 三星显示有限公司 2024-06-07 — — CN disclosed
US-20240147746-A1 ORGANIC COMPOUND AND USE THEREOF WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2024-05-02 — — US disclosed
CN-1816523-A N-(2-phenylethyl)sulfamide derivatives as integrin alpha4 antagonists ALMIRALL PRODESFARMA SA (ES) 2006-08-09 — — CN disclosed
CN-1717629-A Radiation-sensitive resin composition ZEON CORP (JP) 2006-01-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10566543-B2 Pyrimidine derivative and organic electroluminescent devices TYMS, TYMP, DPYD HPRT1 18/4885ALDH1A1 582/4885HSD17B10 2377/4885
US-20110037381-A1 CHRYSENE DERIVATIVE MATERIALS RIF1, CCNL2, ARL1 HPRT1 3889/4885ALDH1A1 766/4885HSD17B10 2078/4885
US-20240147746-A1 ORGANIC COMPOUND AND USE THEREOF PIEZO1, NONO, OR10J3 HPRT1 1922/4885ALDH1A1 1962/4885HSD17B10 3185/4885
US-10686137-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 HPRT1 946/4885ALDH1A1 470/4885HSD17B10 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.