Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628241 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9627780 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9629440 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9713828 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL6907648 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL29368738 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9628428 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL24596055 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9812680 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL9627497 | 0.79 | ALOX5 (0.48) | KDM4EALDH1A1SMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765982-B2 | Synergistic anticoagulant composition | MARSHFIELD CLINIC HEALTH SYSTEM, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110082194-A1 | Synergistic Anticoagulant Composition | WISYS TECHNOLOGY FOUNDATION, INC. | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082194-A1 | Synergistic Anticoagulant Composition | VKORC1L1, VKORC1, F2 | KDM4E 3228/4885ALDH1A1 1993/4885SMN1; SMN2 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.