Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629394 | 0.92 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9628361 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9713446 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9627542 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL24596055 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9812680 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9627596 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL9628130 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL11780453 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL12708461 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |