SCHEMBL1270865

SCHEMBL1270865

CC(C)=C/C=C/C=C(C)C

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
RECQL P46063 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270866 1.00 TSHR (0.30) TSHRALDH1A1ALOX15RECQLHSD17B10
Bicarbonate SCHEMBL8900312 0.84 ALDH1A1 (0.42) TSHRALDH1A1ALOX15RECQLHSD17B10
SCHEMBL8581246 0.82
SCHEMBL18179823 0.82
SCHEMBL8581248 0.82
SCHEMBL14962070 0.82
SCHEMBL21596729 0.82
SCHEMBL20842517 0.82
SCHEMBL21596728 0.82
SCHEMBL7801159 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4282337-A Process for preparing graft polymers of α,α'-disubstituted-β-propiolactones on isobutylene-triene-copolymers ANIC S.P.A. (IT) 1981-08-04 US claimed
US-20170202798-A1 BIPOLAR TRANS CARTENOID SALTS AND THEIR USES DIFFUSION PHARMACEUTICALS LLC (US) 2017-07-20 US disclosed
US-9604899-B2 Bipolar trans carotenoid salts and their uses DIFFUSION PHARMACEUTICALS LLC (US) 2017-03-28 US disclosed
US-8933282-B2 Fuel compositions comprising isoprene derivatives DANISCO US INC. (US) 2015-01-13 US disclosed
US-20140148623-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES DANISCO US INC. (US) 2014-05-29 US disclosed
US-8450549-B2 Fuel compositions comprising isoprene derivatives DANISCO US INC. (US) 2013-05-28 US disclosed
US-20120157725-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES DANISCO US INC. 2012-06-21 US disclosed
EP-2448891-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES Danisco US Inc. (US) 2012-05-09 EP disclosed
US-20110046422-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES DANISCO US INC. 2011-02-24 US disclosed
WO-2010148256-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES DANISCO US INC. (US) 2010-12-23 WO disclosed
EP-1697388-B1 METHOD FOR PRODUCING PHOSPHONIUM SALTS BASF SE (DE) 2010-07-21 EP disclosed
US-4593140-A Catalyst contains nickel and phosphorus compound SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) 1986-06-03 US disclosed
US-4282337-A Process for preparing graft polymers of α,α'-disubstituted-β-propiolactones on isobutylene-triene-copolymers ANIC S.P.A. (IT) 1981-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157725-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES GGPS1, FNTA, FDFT1 TSHR 4501/4885ALDH1A1 1241/4885ALOX15 241/4885
US-20170202798-A1 BIPOLAR TRANS CARTENOID SALTS AND THEIR USES TXNRD2, CYP11B2, CYP11B1 TSHR 1403/4885ALDH1A1 2608/4885ALOX15 505/4885
US-20110046422-A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES GGPS1, FNTA, COASY TSHR 4527/4885ALDH1A1 1476/4885ALOX15 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.