Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583555 | 0.87 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL1154267 | 0.81 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL16638539 | 0.80 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL693651 | 0.80 | RAB9A (0.61) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL6098647 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL920548 | 0.78 | RAB9A (0.63) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL10604932 | 0.75 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL16638538 | 0.75 | RAB9A (0.62) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL1270848 | 0.74 | RAB9A (0.58) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL920481 | 0.74 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862686-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | ADAMA MAKHTESHIM LTD. (IL) | 2018-01-09 | — | — | US | claimed |
| US-20150191436-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2015-07-09 | — | — | US | claimed |
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | claimed |
| EP-2462134-B1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-05-07 | — | — | EP | claimed |
| EP-2462134-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | claimed |
| WO-2011017547-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | claimed |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | claimed |
| US-9862686-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | ADAMA MAKHTESHIM LTD. (IL) | 2018-01-09 | — | — | US | disclosed |
| US-20150191436-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2015-07-09 | — | — | US | disclosed |
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2462134-B1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2462134-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017547-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191436-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DDT, SULT1E1, CYP1A1 | CYP1A2 27/4885CYP3A4 32/4885CYP2C19 518/4885 |
| US-20110034493-A1 | N1-SULFONYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DDT, SULT1E1, CYP1A1 | CYP1A2 27/4885CYP3A4 32/4885CYP2C19 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.