Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098647 | 0.86 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL1154267 | 0.84 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL12585076 | 0.83 | LMNA (0.64) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL1153408 | 0.82 | LMNA (0.56) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL1270965 | 0.80 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL20381747 | 0.80 | RAB9A (0.72) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL8637756 | 0.78 | LMNA (0.49) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL3748894 | 0.78 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL8635319 | 0.78 | RAB9A (0.66) | CYP1A2CYP3A4CYP2C19HPGDRAB9A | |
| SCHEMBL16638538 | 0.78 | RAB9A (0.62) | CYP1A2CYP3A4CYP2C19HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006259-B2 | N1-sulfonyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |