Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711467 | 0.86 | RORC (0.46) | RORCBDKRB2 | |
| SCHEMBL13145077 | 0.81 | BDKRB2 (0.63) | RORCBDKRB2 | |
| SCHEMBL13145056 | 0.81 | BDKRB2 (0.63) | RORCBDKRB2 | |
| SCHEMBL13145076 | 0.81 | BDKRB2 (0.63) | RORCBDKRB2 | |
| SCHEMBL13145052 | 0.81 | BDKRB2 (0.50) | RORCBDKRB2 | |
| SCHEMBL13145040 | 0.81 | BDKRB2 (0.64) | RORCBDKRB2 | |
| SCHEMBL14038584 | 0.79 | RORC (0.42) | RORCBDKRB2 | |
| SCHEMBL13145053 | 0.79 | BDKRB2 (0.52) | RORCBDKRB2 | |
| SCHEMBL14038505 | 0.78 | BDKRB2 (0.43) | BDKRB2 | |
| SCHEMBL12711844 | 0.77 | BDKRB2 (0.59) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305668-A1 | 8-oxy-quinoline derivatives as bradykinin B2 receptor modulators | Jerini AG (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2008116620-A1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2008-10-02 | — | — | WO | disclosed |