SCHEMBL1271191

SCHEMBL1271191

C=Cc1cccc(C(C)C[SiH](OC)OC)c1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PTGS2 P35354 1/20 0.37
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270717 0.81 ALDH1A1 (0.38) TRPA1ALDH1A1TSHR
SCHEMBL2464757 0.80 TP53 (0.43) TP53TDP1PTGS2CYP3A4CYP2D6
SCHEMBL8378966 0.77 HDAC8 (0.49) TP53TDP1PTGS2CYP2C9TRPA1
SCHEMBL11518546 0.77 HDAC8 (0.49) TP53TDP1PTGS2CYP2C9TRPA1
SCHEMBL15562624 0.76 TP53 (0.46) TP53TDP1PTGS2TRPA1ALDH1A1
SCHEMBL9230452 0.75 TAAR1 (0.48) TRPA1ALDH1A1
SCHEMBL8852952 0.74 TP53 (0.44) TP53TDP1PTGS2ALDH1A1TSHR
SCHEMBL7862299 0.74 TP53 (0.47) TP53TDP1PTGS2CYP3A4CYP2D6
SCHEMBL911023 0.73 TP53 (0.54) TP53TDP1PTGS2CYP3A4MAPT
SCHEMBL32671494 0.73 TP53 (0.54) TP53TDP1PTGS2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130037098-A1 INFRARED REFLECTIVE LAMINATE TECHNO POLYMER CO., LTD (JP) 2013-02-14 US disclosed
US-8339700-B2 Infrared reflective laminate TECHNO POLYMER CO., LTD (JP) 2012-12-25 US disclosed
US-20110284071-A1 MULTILAYER BODY Techno- Polymer Co., Ltd. (JP) 2011-11-24 US disclosed
US-20110061720-A1 LAMINATE TECHNO POLYMER CO., LTD. (JP) 2011-03-17 US disclosed
US-20110043901-A1 INFRARED REFLECTIVE LAMINATE TECHNO POLYMER CO., LTD. (JP) 2011-02-24 US disclosed
EP-2279863-A1 LAMINATE Techno Polymer Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20100189975-A1 LAYERED PRODUCT TECHNO POLYMER CO., LTD. (JP) 2010-07-29 US disclosed
EP-2204281-A1 INFRARED REFLECTIVE LAMINATE Techno Polymer Co., Ltd. (JP) 2010-07-07 EP disclosed
US-5605962-A BLEND OF RUBBER REINFORCED RESIN WITH PHENOLIC RESIN AND ORGANOPHOSPHORUS COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-02-25 US disclosed
EP-0578873-B1 Flame-retardant resin composition DSM NV (NL) 1995-12-06 EP disclosed
EP-0612806-A1 Flame retarding resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-08-31 EP disclosed
EP-0578873-A1 Flame-retardant resin composition DSM N.V. (NL) 1994-01-19 EP disclosed