Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491221 | 0.83 | HDAC4 (0.35) | ALDH1A1CYP2D6HDAC4HDAC8HDAC2 | |
| SCHEMBL8378966 | 0.81 | HDAC8 (0.49) | TP53TDP1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL11518546 | 0.81 | HDAC8 (0.49) | TP53TDP1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL1271191 | 0.80 | TP53 (0.40) | TP53TDP1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL15562624 | 0.79 | TP53 (0.46) | TP53TDP1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL699213 | 0.79 | ALDH1A1 (0.42) | TDP1PTGS2TRPA1ALDH1A1TSHR | |
| SCHEMBL8852952 | 0.78 | TP53 (0.44) | TP53TDP1PTGS2ALDH1A1TSHR | |
| SCHEMBL7862299 | 0.77 | TP53 (0.47) | TP53TDP1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL911023 | 0.76 | TP53 (0.54) | TP53TDP1PTGS2TRPA1ALDH1A1 | |
| SCHEMBL32671494 | 0.76 | TP53 (0.54) | TP53TDP1PTGS2TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280130-B2 | Polyisobutylene-based thermoplastic elastomers | THE UNIVERSITY OF AKRON (US) | 2019-05-07 | — | — | US | claimed |
| US-20170240493-A1 | NOVEL POLYISOBUTYLENE-BASED THERMOPLASTIC ELASTOMERS | THE UNIVERSITY OF AKRON (US) | 2017-08-24 | — | — | US | claimed |
| US-20150210810-A1 | Novel Polyisobutylene-Based Thermoplastic Elastomers | THE UNIVERSITY OF AKRON (US) | 2015-07-30 | — | — | US | claimed |
| US-8748530-B2 | Arborescent polymers and process for making same | THE UNIVERSITY OF AKRON (US) | 2014-06-10 | — | — | US | claimed |
| WO-2014025986-A2 | NOVEL POLYISOBUTYLENE-BASED THERMOPLASTIC ELASTOMERS | THE UNIVERSITY OF AKRON (US) | 2014-02-13 | — | — | WO | claimed |
| US-20130303688-A1 | ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME | LANXESS INC (CA) | 2013-11-14 | — | — | US | claimed |
| US-8580917-B2 | Method of purifying block copolymers | THE UNIVERSITY OF AKRON (US) | 2013-11-12 | — | — | US | claimed |
| US-20130261250-A1 | ARBORESCENT POLYMERS HAVING A CORE WITH A HIGH GLASS TRANSITION TEMPERATURE AND PROCESS FOR MAKING SAME | LANXESS INC. (CA) | 2013-10-03 | — | — | US | claimed |
| EP-2019844-B1 | METHOD OF PURIFYING BLOCK COPOLYMERS | UNIV AKRON (US) | 2013-09-11 | — | — | EP | claimed |
| US-20130144021-A1 | ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME | LANXESS, INC. (CA) | 2013-06-06 | — | — | US | claimed |
| EP-2064247-A2 | ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2009-06-03 | — | — | EP | claimed |
| JP-4231777-B2 | — | — | 2009-03-04 | — | — | JP | claimed |
| EP-2019844-A2 | METHOD OF PURIFYING BLOCK COPOLYMERS | The University of Akron (US) | 2009-02-04 | — | — | EP | claimed |
| WO-2008027589-A2 | ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2007136700-A2 | METHOD OF PURIFYING BLOCK COPOLYMERS | THE UNIVERSITY OF AKRON (US) | 2007-11-29 | — | — | WO | claimed |
| JP-2004526857-A | — | — | 2004-09-02 | — | — | JP | claimed |
| US-6747098-B2 | A BRANCHED BLOCK COPOLYMER COMPRISING A LOW GLASS TRANSITION TEMPERATURE SOFT SEGMENTS AND RIGID SEGMENTS WITH A HIGH TRANSITION TEMPERATURE OR CRYSTALLINE MELTING POINT; NON-BIODEGRADABLE IMPLANTABLE PROSTHESUS | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2004-06-08 | — | — | US | claimed |
| EP-1395622-A1 | ARBORESCENT THERMOPLASTIC ELASTOMERS AND PRODUCTS THEREFROM | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2004-03-10 | — | — | EP | claimed |
| US-20030065098-A1 | Arborescent thermoplastic elastomers and products therefrom | AUSTIN VENTURE PARTNERS, LLC | 2003-04-03 | — | — | US | claimed |
| WO-2002096967-A1 | ARBORESCENT THERMOPLASTIC ELASTOMERS AND PRODUCTS THEREFROM | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2002-12-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210810-A1 | Novel Polyisobutylene-Based Thermoplastic Elastomers | TERB1, TERT, TRRAP | TP53 2766/4885TDP1 334/4885PTGS2 2326/4885 |
| US-20170240493-A1 | NOVEL POLYISOBUTYLENE-BASED THERMOPLASTIC ELASTOMERS | TERB1, TERT, TRRAP | TP53 2766/4885TDP1 334/4885PTGS2 2326/4885 |
| US-10280130-B2 | Polyisobutylene-based thermoplastic elastomers | TERB1, TRRAP, RPIA | TP53 2612/4885TDP1 295/4885PTGS2 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.