SCHEMBL127126

SCHEMBL127126

CN(C)c1nc(N)c(N)c(N)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
CYP1A2 P05177 1/20 0.56
THRB P10828 1/20 0.56
BLM P54132 1/20 0.56
CREBBP Q92793 1/20 0.56
HSD17B10 Q99714 1/20 0.56
GAA P10253 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 2/20 0.41
GLA P06280 1/20 0.41
SMARCA2 P51531 1/20 0.41
ALDH1A1 P00352 8/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HTT P42858 1/20 0.32
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL2854099 0.86 LMNA (0.42) LMNACYP1A2THRBBLMCREBBP
SCHEMBL11511553 0.85 LMNA (0.46) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10485417 0.79 LMNA (0.40) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10485636 0.76 LMNA (0.37) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10485322 0.75 ALDH1A1 (0.39) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10485405 0.75 ALDH1A1 (0.42) LMNACYP1A2THRBBLMCREBBP
SCHEMBL10752491 0.74 LMNA (0.53) LMNACYP1A2THRBBLMCREBBP
SCHEMBL6456004 0.74 LMNA (0.46) LMNACYP1A2THRBBLMCREBBP
SCHEMBL16093989 0.74 LMNA (0.46) LMNACYP1A2THRBBLMCREBBP
Altretamine SCHEMBL2354769 0.73 LMNA (1.00) LMNACYP1A2THRBBLMCREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440174-B1 AFTERTREATMENT FOR COLOR FIXATION HENKEL AG & CO KGAA (DE) 2014-12-17 EP claimed
EP-1787685-B1 Combinations of dye precursors HENKEL AG & CO KGAA (DE) 2013-12-25 EP claimed
US-8349023-B2 After treatment for color fixation HENKEL AG & CO. KGAA (DE) 2013-01-08 US claimed
EP-2440174-A2 AFTERTREATMENT FOR COLOR FIXATION Henkel AG & Co. KGaA (DE) 2012-04-18 EP claimed
US-20120080046-A1 After Treatment for Color Fixation HENKEL AG & CO. KGAA (DE) 2012-04-05 US claimed
WO-2010142493-A2 AFTERTREATMENT FOR COLOR FIXATION HENKEL AG & CO. KGAA (DE) 2010-12-16 WO claimed
EP-1443890-B1 OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS HENKEL AG & CO KGAA (DE) 2010-01-13 EP claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US claimed
EP-1909913-A1 METHOD FOR QUICKLY CONCEALING THE ROOTS OF HAIR THAT HAVE GROWN AFTER THE HAIR HAS BEEN DYED HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-04-16 EP claimed
EP-1286647-B1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KGAA (DE) 2008-01-09 EP claimed
WO-2002010118-A1 OXIDIZING COLORANT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO claimed
WO-2001097756-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
EP-1040817-A1 Dyeing composition comprising a pyrazolo(1,5-a)pyrimidine and a monocyclic polyaminopyrimidine as oxidation bases and a coupler, and dyeing process L'OREAL (FR) 2000-10-04 EP claimed
US-4900325-A AMINODIPHENYLAMINE COUPLERS, TETRAAMINOPYRIMIDINE DEVELOPERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-02-13 US claimed
US-RE30199-E Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-01-29 US claimed
US-4171203-A IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-10-16 US claimed
US-4168953-A Oxidation hair dyes based upon tetraaminopyrimidine developers and monohydroxyindazole couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-09-25 US claimed
US-4129414-A Oxidation hair colorants containing water-soluble polyhalogen 3-aminophenols as couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1978-12-12 US claimed
US-4129413-A Oxidation hair dyes based upon tetraaminopyrimidine developers and mono- and dialkyl -m- dihydroxy benzene couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1978-12-12 US claimed
US-4003699-A Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL & CIE G.M.B.H. (DT) 1977-01-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080046-A1 After Treatment for Color Fixation TYR, NAT1, KAT2A LMNA 168/4885CYP1A2 407/4885THRB 2394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.