Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.37 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712985 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2PDE2APSEN1PSEN2APH1B | |
| SCHEMBL12712982 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2PDE2APSEN1PSEN2APH1B | |
| SCHEMBL12712984 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2PDE2APSEN1PSEN2APH1B | |
| SCHEMBL1237513 | 0.83 | PSEN1 (0.45) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1237516 | 0.83 | PSEN1 (0.45) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14870575 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2PDE2AALDH1A1CCR2HTT | |
| SCHEMBL1239910 | 0.82 | PSEN1 (0.45) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1239908 | 0.82 | PSEN1 (0.45) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1238768 | 0.82 | PSEN1 (0.46) | SMN1; SMN2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14870584 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2PDE2APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086860-A1 | COMPOUND | KIMURA TEIJI | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086860-A1 | COMPOUND | ARRB1, NR3C2, ADRA2C | SMN1; SMN2 1928/4885PDE2A 1530/4885PSEN1 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.