Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12713460 | 0.90 | LMNA (0.53) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713391 | 0.87 | LMNA (0.64) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713395 | 0.86 | LMNA (0.69) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713397 | 0.86 | LMNA (0.63) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713425 | 0.85 | LMNA (0.78) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713398 | 0.83 | LMNA (0.59) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713469 | 0.79 | LMNA (0.56) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713388 | 0.78 | LMNA (0.63) | LMNAMAPTRXFP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18883830 | 0.77 | LMNA (0.50) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL12713389 | 0.77 | LMNA (0.55) | LMNAMAPTNPSR1RXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657031-B2 | Ant-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2017-05-23 | — | — | US | disclosed |
| US-9657031-B2 | Ant-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2017-05-23 | — | — | US | disclosed |
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2014-11-27 | — | — | US | disclosed |
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2014-11-27 | — | — | US | disclosed |
| US-8809346-B2 | ANT-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2014-08-19 | — | — | US | disclosed |
| US-8809346-B2 | ANT-ligands molecules and biological applications | UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) | 2014-08-19 | — | — | US | disclosed |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2011-04-14 | — | — | US | disclosed |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | MITOLOGICS (FR) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350033-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | CXCR3, ACKR3, CCR3 | LMNA 2370/4885MAPT 4797/4885NPSR1 95/4885 |
| US-20110086865-A1 | ANT-LIGANDS MOLECULES AND BIOLOGICAL APPLICATIONS | CXCR3, ACKR3, CCR3 | LMNA 2515/4885MAPT 4805/4885NPSR1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.