Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.65 |
| ▸ | ADK | P55263 | 14/20 | 0.56 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19271869 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL6723537 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL1573050 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13649996 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13021352 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL2786078 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13650003 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL15241432 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13091999 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL6723371 | 0.91 | ADK (0.65) | ADORA2AADKHASPINADORA3MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195326-B1 | NUCLEOSIDE DERIVATIVES AS INHIBITORS OF VIRAL POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2011-04-13 | — | — | EP | disclosed |