Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.65 |
| ▸ | ADK | P55263 | 14/20 | 0.56 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723537 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL1573050 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13649996 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13021352 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL2786078 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL12716058 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13650003 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL15241432 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL13091999 | 1.00 | ADORA2A (0.65) | ADORA2AADKHASPINADORA3ADORA2B | |
| SCHEMBL6723371 | 0.91 | ADK (0.65) | ADORA2AADKHASPINADORA3MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240584-A1 | NOVEL 7-DEAZAPURINE NUCLEOSIDES FOR THERAPEUTIC USES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR,V.V.I. (CZ) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240584-A1 | NOVEL 7-DEAZAPURINE NUCLEOSIDES FOR THERAPEUTIC USES | TPMT, TYMP, ENTPD5 | ADORA2A 54/4885ADK 272/4885HASPIN 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.