Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 5/20 | 0.37 |
| ▸ | CASP6 | P55212 | 3/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12745899 | 0.86 | KDM4E (0.48) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL18215408 | 0.84 | KDM4E (0.49) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL22753433 | 0.81 | KDM4E (0.47) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL3216951 | 0.81 | MAPT (0.50) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL22307835 | 0.80 | MAPT (0.46) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL22307836 | 0.80 | KDM4E (0.52) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL22308325 | 0.78 | MAPT (0.49) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL18678090 | 0.78 | KDM4E (0.44) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL21361931 | 0.77 | KDM4E (0.47) | KDM4EMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL3410954 | 0.77 | MAPT (0.48) | KDM4EMAPTALDH1A1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923433-B2 | Activity-based probes and methods of their preparation and use | ACTIVX BIOSCIENCES, INC. (US) | 2011-04-12 | — | — | US | disclosed |
| US-20070141624-A1 | ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE | ACTIVX BIOSCIENCES, INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141624-A1 | ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE | DNPEP, CTRL, ARSA | KDM4E 4087/4885MAPT 2754/4885ALDH1A1 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.