SCHEMBL12716601

SCHEMBL12716601

c1ccc(-n2c3cc(-c4ccc5c6c(cccc46)-c4ccccc4-5)ccc3c3ccc(-c4ccc5c6c(cccc46)-c4ccccc4-5)cc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ATM Q13315 1/20 0.46
KEAP1 Q14145 3/20 0.39
NFE2L2 Q16236 3/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
ALDH1A1 P00352 7/20 0.38
MAPK1 P28482 2/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
CASP1 P29466 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KMT2A Q03164 4/20 0.36
USP2 O75604 3/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12716591 0.97 L3MBTL1 (0.51) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL17953767 0.96 L3MBTL1 (0.50) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL17953775 0.93 L3MBTL1 (0.47) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL17953796 0.93 L3MBTL1 (0.47) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL17953778 0.93 L3MBTL1 (0.50) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL15480183 0.92 L3MBTL1 (0.46) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL12716616 0.92 L3MBTL1 (0.39) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL17953784 0.92 L3MBTL1 (0.49) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL17953776 0.92 L3MBTL1 (0.49) KDM4EL3MBTL1ATMKEAP1NFE2L2
SCHEMBL15480184 0.92 L3MBTL1 (0.49) KDM4EL3MBTL1ATMKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923129-B2 extremely high efficiency and a high luminance and has an extremely high durability; 2-pyrenylcarbazoles; blue CANON KABUSHIKI KAISHA (JP) 2011-04-12 US disclosed
US-7923129-B2 extremely high efficiency and a high luminance and has an extremely high durability; 2-pyrenylcarbazoles; blue CANON KABUSHIKI KAISHA (JP) 2011-04-12 US disclosed
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-06-05 US disclosed
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME OXA1L, CYP2C19, PPOX KDM4E 2753/4885L3MBTL1 873/4885ATM 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.