Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396071 | 0.89 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL21952075 | 0.89 | MEN1 (0.65) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL22010389 | 0.86 | HPGD (0.69) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL21952070 | 0.85 | MEN1 (0.61) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL31396394 | 0.85 | MEN1 (0.61) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL21952060 | 0.83 | KMT2A (0.58) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL31396269 | 0.83 | KMT2A (0.58) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL21952023 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL31396267 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1MAPK1NPSR1 | |
| SCHEMBL21952093 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928113-B2 | Integrin-binding small molecules | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7928113-B2 | Integrin-binding small molecules | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-04-19 | — | — | US | disclosed |
| US-20070155750-A1 | INTEGRIN-BINDING SMALL MOLECULES | USC STEVENS-UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-07-05 | — | — | US | disclosed |
| US-20070155750-A1 | INTEGRIN-BINDING SMALL MOLECULES | USC STEVENS-UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-07-05 | — | — | US | disclosed |
| WO-2007059195-A1 | INTEGRIN-BINDING SMALL MOLECULES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155750-A1 | INTEGRIN-BINDING SMALL MOLECULES | ITGB3, ITGB5, ITGA2B | MEN1 4015/4885KMT2A 4552/4885ALDH1A1 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.