Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12822962 | 0.95 | PTGS2 (0.39) | MEN1KMT2AS1PR1S1PR3PTGS2 | |
| SCHEMBL12719083 | 0.89 | S1PR1 (0.38) | MEN1KMT2AS1PR1S1PR3FFAR1 | |
| SCHEMBL10303036 | 0.89 | FFAR4 (0.35) | MEN1KMT2AS1PR1S1PR3PTGS2 | |
| SCHEMBL12823853 | 0.88 | MEN1 (0.43) | MEN1KMT2APTGS2FFAR1FFAR4 | |
| SCHEMBL12822519 | 0.88 | PTGS2 (0.40) | KMT2AS1PR1S1PR3PTGS2ADRB2 | |
| SCHEMBL12719076 | 0.88 | S1PR1 (0.37) | MEN1KMT2AS1PR1S1PR3FFAR1 | |
| SCHEMBL12823457 | 0.86 | ESR1 (0.36) | ADRB2RARB | |
| SCHEMBL12740170 | 0.85 | S1PR1 (0.39) | S1PR1S1PR3FFAR1FFAR4RARB | |
| SCHEMBL14766910 | 0.85 | FFAR1 (0.43) | S1PR1S1PR3FFAR1FFAR4 | |
| SCHEMBL13586170 | 0.85 | FFAR4 (0.35) | MEN1KMT2AS1PR1S1PR3FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305627-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |