Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717002 | 0.91 | FFAR4 (0.35) | FFAR4MEN1KMT2AFAAHNPSR1 | |
| SCHEMBL13586170 | 0.91 | FFAR4 (0.35) | FFAR4MEN1KMT2AFAAHNPSR1 | |
| SCHEMBL10303076 | 0.89 | CNR2 (0.35) | ADRB1GABRA1GABRB2S1PR1 | |
| SCHEMBL10303039 | 0.89 | CNR2 (0.37) | ADRB1GABRA1GABRB2S1PR1S1PR3 | |
| SCHEMBL12718554 | 0.89 | MEN1 (0.40) | FFAR4PTGS2MEN1KMT2AFAAH | |
| SCHEMBL10303067 | 0.89 | PTGS2 (0.39) | FFAR4PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL10303207 | 0.88 | FFAR1 (0.39) | PTGS2PTGS1MEN1KMT2AFAAH | |
| SCHEMBL10303034 | 0.86 | ADRB2 (0.35) | ADRB2ADRB1 | |
| SCHEMBL12718504 | 0.86 | FAAH (0.42) | FFAR4PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL10303179 | 0.85 | FFAR1 (0.40) | FFAR4PTGS2PTGS1FAAHPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216489-B2 | Three-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |