Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 6/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12823012 | 0.87 | DRD4 (0.32) | GPR119DRD4SIGMAR1TMEM97DRD3 | |
| SCHEMBL12822552 | 0.87 | GPR119 (0.30) | GPR119 | |
| SCHEMBL12823100 | 0.86 | DRD4 (0.36) | DRD4SIGMAR1TMEM97 | |
| SCHEMBL13586568 | 0.85 | HTR1A (0.31) | — | |
| SCHEMBL12719392 | 0.85 | FFAR1 (0.35) | KDM5AKDM4CBRD4 | |
| SCHEMBL12718709 | 0.84 | PDE4A (0.33) | BRD4 | |
| SCHEMBL12718251 | 0.84 | OPRL1 (0.34) | BRD4 | |
| SCHEMBL12718399 | 0.83 | BRD4 (0.34) | BRD4 | |
| SCHEMBL12718774 | 0.83 | HTR1A (0.33) | — | |
| SCHEMBL12823784 | 0.83 | OPRL1 (0.33) | GPR119KDM5AKDM4CBRD4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305627-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |