Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 9/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720135 | 0.96 | F2R (0.52) | F2RCNR1TMEM97POLBEPHX2 | |
| SCHEMBL12720052 | 0.88 | F2R (0.49) | F2RCNR1TMEM97POLBEPHX2 | |
| SCHEMBL641144 | 0.85 | F2R (0.62) | F2RCNR1TMEM97POLBEPHX2 | |
| SCHEMBL12720043 | 0.85 | F2R (0.53) | F2RCNR1TMEM97POLBEPHX2 | |
| SCHEMBL12720040 | 0.84 | F2R (0.54) | F2RCNR1TMEM97EPHX2KDM2B | |
| SCHEMBL12720147 | 0.83 | F2R (0.51) | F2RCNR1TMEM97EPHX2ABL1 | |
| SCHEMBL13808304 | 0.83 | F2R (0.53) | F2RCNR1TMEM97EPHX2 | |
| SCHEMBL12720114 | 0.83 | F2R (0.51) | F2RCNR1TMEM97EPHX2ABL1 | |
| SCHEMBL643326 | 0.82 | F2R (0.65) | F2RCNR1TMEM97EPHX2ABL1 | |
| SCHEMBL13808409 | 0.82 | F2R (0.51) | F2RCNR1TMEM97ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |