SCHEMBL127203

SCHEMBL127203

O=C(NC1CCCCCCC1)c1ccc2cc(C(=O)NC3CCCCCCC3)ccc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.65
RAB9A P51151 10/20 0.65
SMN1; SMN2 Q16637 4/20 0.65
HPGD P15428 3/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C19 P33261 1/20 0.65
TP53 P04637 1/20 0.63
NFKB1 P19838 1/20 0.63
NFKB2 Q00653 1/20 0.63
RELA Q04206 1/20 0.63
SMYD3 Q9H7B4 1/20 0.61
HRH3 Q9Y5N1 1/20 0.60
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
ALDH1A1 P00352 1/20 0.58
TSHR P16473 1/20 0.58
LMNA P02545 1/20 0.58
HPGDS O60760 1/20 0.58
KDM4E B2RXH2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28658639 1.00 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL124356 1.00 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517344 1.00 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL29380975 1.00 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL518025 0.98 SMYD3 (0.63) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL22494493 0.95 NPC1 (0.59) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517341 0.95 NPC1 (0.63) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL3031654 0.94 NPC1 (0.58) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL7928067 0.94 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL29818792 0.94 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11733189-B2 Method for identifying a blend of nucleators useful for preparing a nucleated polyolefin material NJC EUROPE LIMITED (GB) 2023-08-22 US claimed
WO-2021069690-A1 FILM THAI POLYETHYLENE CO., LTD. (TH) 2021-04-15 WO claimed
US-20190219528-A1 METHOD FOR IDENTIFYING A BLEND OF NUCLEATORS USEFUL FOR PREPARING A NUCLEATED POLYOLEFIN MATERIAL NJC EUROPE LIMITED (GB) 2019-07-18 US claimed
US-10011709-B2 Compositions comprising propylene-based elastomers and polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-07-03 US claimed
US-20170362421-A1 Compositions Comprising Propylene-Based Elastomers and Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-12-21 US claimed
WO-2017182804-A1 METHOD FOR IDENTIFYING A BLEND OF NUCLEATORS USEFUL FOR PREPARING A NUCLEATED POLYOLEFIN MATERIAL NJC EUROPE LIMITED (GB) 2017-10-26 WO claimed
WO-2016137559-A1 COMPOSITIONS COMPRISING PROPYLENE-BASED ELASTOMERS AND POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-01 WO claimed
US-6235823-B1 CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-05-22 US claimed
EP-0557721-B1 Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. NEW JAPAN CHEM CO LTD (JP) 2000-10-04 EP claimed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP claimed
EP-4667512-A1 INCREASED AREA STRETCH RATIO FOR CAPACITOR FILMS MADE OF A BIAXIALLY ORIENTED POLYPROPYLENE FILM Borealis GmbH (AT) 2025-12-24 EP disclosed
WO-2025083226-A1 METHOD FOR ADDING ADDITIVES TO A POLYOLEFIN MELT OR A POLYOLEFIN SOLUTION BOREALIS AG (AT) 2025-04-24 WO disclosed
EP-4491396-A1 COMPOSITION COMPRISING POLYPROPYLENE AND CYCLIC OLEFIN POLYMER WITH IMPROVED DISPERSION PROPERTIES AND BREAKDOWN PERFORMANCE Borealis AG (AT) 2025-01-15 EP disclosed
EP-4086299-B1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM BOREALIS AG (AT) 2024-07-03 EP disclosed
US-20240199865-A1 POLYPROPYLENE COMPOSITION FOR CABLE INSULATION BOREALIS AG (AT) 2024-06-20 US disclosed
EP-1260546-A1 Polyolefin multilayer pipe Borealis Technology OY (FI) 2002-11-27 EP disclosed
US-6235823-B1 CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-05-22 US disclosed
EP-0557721-B1 Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. NEW JAPAN CHEM CO LTD (JP) 2000-10-04 EP disclosed
EP-0962489-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-12-08 EP disclosed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP disclosed