SCHEMBL517341

SCHEMBL517341

O=C(NC1CCCCC1)c1ccc2ccc(C(=O)NC3CCCCC3)cc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.63
RAB9A P51151 9/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
HPGD P15428 2/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C19 P33261 1/20 0.63
TP53 P04637 1/20 0.61
NFKB1 P19838 1/20 0.61
NFKB2 Q00653 1/20 0.61
RELA Q04206 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.58
ALDH1A1 P00352 1/20 0.57
TSHR P16473 1/20 0.57
LMNA P02545 1/20 0.57
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56
GFER P55789 1/20 0.56
HSD17B10 Q99714 1/20 0.56
SMYD3 Q9H7B4 1/20 0.56
HRH3 Q9Y5N1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127203 0.95 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL124356 0.95 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL517344 0.95 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL29380975 0.95 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL28658639 0.95 NPC1 (0.65) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL3034498 0.94 NPC1 (0.56) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL518025 0.93 SMYD3 (0.63) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL7928067 0.92 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL29818792 0.92 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDCYP1A2
SCHEMBL22494493 0.90 NPC1 (0.59) NPC1RAB9ASMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127142-B2 Low temperature injection molding of polyarylene sulfide compositions TICONA LLC (US) 2015-09-08 US claimed
US-9102792-B2 High performance polymer composition with improved flow properties TICONA LLC (US) 2015-08-11 US claimed
US-9080036-B2 Nucleating system for polyarylene sulfide compositions TICONA LLC (US) 2015-07-14 US claimed
US-9057016-B2 Melt polymerization of low melt viscosity liquid crystalline polymers TICONA LLC (US) 2015-06-16 US claimed
US-9051514-B2 High flow liquid crystalline polymer composition TICONA LLC (US) 2015-06-09 US claimed
US-9045685-B2 Cast molded parts formed from a liquid crystalline polymer TICONA LLC (US) 2015-06-02 US claimed
US-8906258-B2 Heat-resistant liquid crystalline polymer composition having a low melting temperature TICONA LLC (US) 2014-12-09 US claimed
US-20140350156-A1 Low Temperature Injection Molding of Polyarylene Sulfide Compositions TICONA LLC (US) 2014-11-27 US claimed
EP-2791232-A1 NUCLEATING SYSTEM FOR POLYARYLENE SULFIDE COMPOSITIONS Ticona LLC (US) 2014-10-22 EP claimed
US-20140242385-A1 Liquid Crystalline Polymer Fibers TICONA LLC (US) 2014-08-28 US claimed
WO-2013090171-A1 NUCLEATING SYSTEM FOR POLYARYLENE SULFIDE COMPOSITIONS TICONA LLC (US) 2013-06-20 WO claimed
US-20130158212-A1 Low Temperature Injection Molding of Polyarylene Sulfide Compositions TICONA LLC (US) 2013-06-20 US claimed
US-20130157033-A1 Nucleating System for Polyarylene Sulfide Compositions TICONA LLC (US) 2013-06-20 US claimed
US-20130155597-A1 Molded Part for a Portable Electronic Device TICONA LLC (US) 2013-06-20 US claimed
US-20130062558-A1 Cast Molded Parts Formed from a Liquid Crystalline Polymer TICONA LLC (US) 2013-03-14 US claimed
US-20130053532-A1 Melt Polymerization of Low Melt Viscosity Liquid Crystalline Polymers TICONA LLC (US) 2013-02-28 US claimed
US-20130048908-A1 Heat-Resistant Liquid Crystalline Polymer Composition having a Low Melting Temperature TICONA LLC (US) 2013-02-28 US claimed
US-20130052447-A1 Liquid Crystalline Polymer Composition Containing a Fibrous Filler TICONA LLC (US) 2013-02-28 US claimed
US-20130048914-A1 High Flow Liquid Crystalline Polymer Composition TICONA LLC (US) 2013-02-28 US claimed
US-20130053531-A1 Method for Minimizing Process Disruptions During Formation of a Liquid Crystalline Polymer TICONA LLC (US) 2013-02-28 US claimed