Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127203 | 0.95 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL124356 | 0.95 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL28658639 | 0.95 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL517344 | 0.95 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29380975 | 0.95 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL518025 | 0.93 | SMYD3 (0.63) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL517341 | 0.90 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29818792 | 0.89 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL3031654 | 0.89 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7928067 | 0.89 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999454-B | High-toughness polypropylene composite material capable of inhibiting space charge and preparation method thereof | 清华大学 | 2022-08-30 | — | — | CN | claimed |
| US-11591450-B2 | Method for stabilizing halogen-free thermoplastic recyclates, stabilized plastic compositions, and molding compounds and molded parts produced therefrom | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-02-28 | — | — | US | disclosed |
| CN-115362142-A | Use of substituted cinnamates as stabilizers for organic materials, stabilized organic materials, methods of stabilizing organic materials, and specific cinnamates | 弗劳恩霍夫应用研究促进协会 | 2022-11-18 | — | — | CN | disclosed |
| US-11407720-B2 | Compounds having a stabilizing effect, method for producing said compounds, composition containing said stabilizing compounds, and uses of the compounds | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2022-08-09 | — | — | US | disclosed |
| US-11358941-B2 | — | — | 2022-06-14 | — | — | US | disclosed |
| US-20220119624-A1 | METHOD OF STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, PLASTICS COMPOSITION, STABILIZER COMPOSITION AND USE OF THE STABILIZER COMPOSITION | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2022-04-21 | — | — | US | disclosed |
| US-20200361879-A1 | COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2020-11-19 | — | — | US | disclosed |
| US-20200317886-A1 | METHOD FOR STABILIZING HALOGEN-FREE THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407720-B2 | Compounds having a stabilizing effect, method for producing said compounds, composition containing said stabilizing compounds, and uses of the compounds | OGG1, SOD1, ERCC5 | NPC1 949/4885RAB9A 2514/4885SMN1; SMN2 322/4885 |
| US-11358941-B2 | — | OGG1, SOD1, ERCC5 | NPC1 1301/4885RAB9A 2784/4885SMN1; SMN2 589/4885 |
| US-20200361879-A1 | COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS | OGG1, SOD1, AOX1 | NPC1 1138/4885RAB9A 2832/4885SMN1; SMN2 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.