Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 4/20 | 0.41 |
| ▸ | NMT1 | P30419 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1582654 | 0.99 | NMT2 (0.41) | NMT2NMT1KCNH2GRIN2B | |
| SCHEMBL12720559 | 0.91 | NMT2 (0.42) | NMT2NMT1GRIN2B | |
| Hydrochloric Acid SCHEMBL1582749 | 0.90 | NMT2 (0.42) | NMT2NMT1GRIN2B | |
| SCHEMBL1582985 | 0.90 | KCNH2 (0.42) | NMT2NMT1KCNH2GRIN2B | |
| Hydrochloric Acid SCHEMBL1582048 | 0.88 | KCNH2 (0.39) | NMT2NMT1KCNH2GRIN2B | |
| SCHEMBL12720516 | 0.86 | NMT2 (0.44) | NMT2NMT1 | |
| Hydrochloric Acid SCHEMBL1582973 | 0.86 | NMT2 (0.43) | NMT2NMT1 | |
| Hydrochloric Acid SCHEMBL1582698 | 0.82 | NMT2 (0.40) | NMT2NMT1 | |
| SCHEMBL1582816 | 0.80 | DRD2 (0.39) | NMT2NMT1KCNH2GRIN2B | |
| SCHEMBL1582770 | 0.79 | KCNH2 (0.40) | NMT2NMT1KCNH2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | disclosed |