Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12722187 | 0.82 | TSHR (0.46) | SLC6A9KDM4EGAAMAPK1TSHR | |
| SCHEMBL12722186 | 0.81 | TDP1 (0.40) | SLC6A9KDM4EGAAMAPK1TSHR | |
| SCHEMBL6542262 | 0.76 | ALDH1A1 (0.55) | GAATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22048701 | 0.76 | KMT2A (0.47) | KDM4EGAAMAPK1TSHRSMN1; SMN2 | |
| Acetic Acid SCHEMBL10997412 | 0.75 | MAPT (0.51) | KDM4EGAAMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL20522075 | 0.74 | GAA (0.61) | GAATSHRL3MBTL1MAPTPKM | |
| SCHEMBL12722182 | 0.73 | GLA (0.41) | KDM4EGAAMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL12722708 | 0.71 | FFAR1 (0.45) | L3MBTL1ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL13607848 | 0.71 | DHODH (0.53) | KDM4EGAATSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL3781671 | 0.70 | MAPT (0.54) | KDM4EGAATSHRSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043480-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2011-04-14 | — | — | WO | disclosed |