Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980139 | 0.82 | CSNK2A1 (0.40) | KMT2AMAPTKDM4EHPGDCSNK2A1 | |
| SCHEMBL19980436 | 0.82 | HTR2C (0.41) | KMT2AMAPTHTR2CHTR2BKDM4E | |
| SCHEMBL21156315 | 0.80 | ALDH1A1 (0.35) | KMT2AMAPTL3MBTL1KDM4EHPGD | |
| SCHEMBL19980376 | 0.79 | CYP19A1 (0.43) | KMT2AMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL19655565 | 0.78 | ALDH1A1 (0.42) | KMT2AMAPTPKML3MBTL1HTR2C | |
| SCHEMBL20344564 | 0.78 | CYP19A1 (0.35) | KMT2AMAPTKDM4EHPGDCSNK2A1 | |
| SCHEMBL20344535 | 0.77 | CYP1A2 (0.44) | MAPTKDM4EHPGDALDH1A1POLB | |
| SCHEMBL14785176 | 0.76 | KMT2A (0.56) | KMT2AMAPTPKML3MBTL1HTR2C | |
| SCHEMBL30304115 | 0.76 | KMT2A (0.56) | KMT2AMAPTPKML3MBTL1HTR2C | |
| SCHEMBL12722178 | 0.76 | SLC6A9 (0.46) | MAPTPKML3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375780-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-06-03 | — | — | EP | disclosed |