SCHEMBL127249

SCHEMBL127249

O=C(CC(=O)c1ccc(O)cc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.77
KMT2A Q03164 5/20 0.77
HPGD P15428 3/20 0.77
MAPT P10636 3/20 0.77
MAPK1 P28482 3/20 0.77
CYP3A4 P08684 2/20 0.77
KDM4E B2RXH2 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
ALOX15 P16050 2/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
CES1 P23141 1/20 0.77
RAB9A P51151 4/20 0.67
NPC1 O15118 3/20 0.67
CES2 O00748 1/20 0.64
ALDH1A1 P00352 3/20 0.61
PLOD2 O00469 2/20 0.61
HIF1A Q16665 2/20 0.61
PLOD3 O60568 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2005451 0.91 MEN1 (0.94) MEN1KMT2AHPGDMAPTMAPK1
SCHEMBL3987484 0.91 NPC1 (0.65) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL1704711 0.88 MEN1 (1.00) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL39582 0.88 MEN1 (1.00) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL10356288 0.88 MEN1 (1.00) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL1628627 0.85 MEN1 (0.94) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL6598370 0.85 MEN1 (0.94) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL531257 0.85 MEN1 (0.94) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL21597905 0.85 MEN1 (0.94) MEN1KMT2AHPGDMAPTMAPK1
Dibenzoylmethane SCHEMBL9493785 0.85 MAPT (0.94) MEN1KMT2AHPGDMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1077 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020068665-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN FABIUS BIOTECHNOLOGY (US) 2020-04-02 WO claimed
EP-2263788-B1 A PROCESS FOR THE PREPARATION OF MICROCAPSULES FILLED WITH ACTIVE INGREDIENTS SOL GEL TECH LTD (IL) 2018-07-25 EP claimed
EP-1656199-B1 MICROCAPSULES LOADED WITH ACTIVE INGREDIENTS AND A METHOD FOR THEIR PREPARATION SOL GEL TECHNOLOGIES LTD (IL) 2016-01-06 EP claimed
WO-2013138637-A1 ROBUST, ULTRAVIOLET-PROTECTED AMBIENT CONDITION HISTORY INDICATOR AND METHOD OF MAKING SAME TEMPTIME CORPORATION (US) 2013-09-19 WO claimed
US-20130239874-A1 ROBUST, ULTRAVIOLET-PROTECTED AMBIENT CONDITION HISTORY INDICATOR AND METHOD OF MAKING SAME TEMPTIME CORPORATION (US) 2013-09-19 US claimed
EP-1104287-B9 METHOD FOR THE PREPARATION OF OXIDE MICROCAPSULES LOADED WITH FUNCTIONAL MOLECULES AND THE PRODUCTS OBTAINED THEREOF SOL GEL TECHNOLOGIES LTD (IL) 2012-12-19 EP claimed
EP-1104287-B1 METHOD FOR THE PREPARATION OF OXIDE MICROCAPSULES LOADED WITH FUNCTIONAL MOLECULES AND THE PRODUCTS OBTAINED THEREOF SOL GEL TECHNOLOGIES LTD (IL) 2012-02-22 EP claimed
US-8110284-B2 Microcapsules loaded with active ingredients and a method for their preparation SOL-GEL TECHNOLOGIES LTD. (IL) 2012-02-07 US claimed
EP-1181001-B1 SUNSCREEN COMPOSITION CONTAINING SOL-GEL MICROCAPSULES SOL GEL TECHNOLOGIES LTD (IL) 2011-07-13 EP claimed
EP-2263788-A2 Microcapsules loaded with active ingredients and a method for their preparation Sol-Gel Technologies Ltd. (IL) 2010-12-22 EP claimed
US-4937370-A ABSORB UVA AND UVB WAVELENGTH RADIATION THE PROCTER & GAMBLE COMPANY (US) 1990-06-26 US claimed
US-4919934-A Cosmetic sticks RICHARDSON-VICKS INC. (US) 1990-04-24 US claimed
US-4869897-A SUNCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-09-26 US claimed
US-4847072-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US claimed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0313303-A2 Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0313347-A2 Photoprotection compositions comprising sorbohydroxamic acid and an anti-inflammatory agent THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0313302-A2 Photoprotection compositions comprising sorbohydroxamic acid THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0313304-A2 Photoprotection compositions comprising tocopherol sorbate THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0251398-A2 Novel chromophores, sunscreen compositions and methods for preventing sunburn THE PROCTER & GAMBLE COMPANY (US) 1988-01-07 EP claimed