Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | BCR | P11274 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 7/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.40 |
| ▸ | IGF1R | P08069 | 6/20 | 0.40 |
| ▸ | SYK | P43405 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1641763 | 0.99 | ALDH1A2 (0.42) | ALDH1A2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL12766425 | 0.95 | SYK (0.46) | ALDH1A2ABL1BCRPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL1640445 | 0.94 | SYK (0.46) | ALDH1A2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL13815935 | 0.85 | CYP3A4 (0.35) | ALDH1A2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL12726554 | 0.83 | IKBKB (0.46) | ABL1PDGFRBPDGFRAEGFRERBB2 | |
| Hydrochloric Acid SCHEMBL1641781 | 0.82 | IKBKB (0.45) | ABL1PDGFRBPDGFRAEGFRERBB2 | |
| SCHEMBL12766551 | 0.80 | BRAF (0.53) | BRAFEGFRERBB2IGF1RSYK | |
| SCHEMBL12766967 | 0.77 | IKBKB (0.46) | ABL1PDGFRBPDGFRAEGFRERBB2 | |
| SCHEMBL1642023 | 0.77 | LCLAT1 (0.47) | ALDH1A2ABL1BCRPDGFRBPDGFRA | |
| SCHEMBL1641931 | 0.77 | IGF1R (0.53) | ABL1BCRPDGFRBPDGFRAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098296-A1 | Thiazole And Oxazole Kinase Inhibitors | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
| US-20110098296-A1 | Thiazole And Oxazole Kinase Inhibitors | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098296-A1 | Thiazole And Oxazole Kinase Inhibitors | PDXK, MAP3K1, MAP4K2 | ALDH1A2 2573/4885ABL1 77/4885BCR 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.