Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12800328 | 0.91 | TLR7 (0.58) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12305188 | 0.89 | CYP3A4 (0.65) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12800329 | 0.84 | TLR7 (0.70) | TLR7 | |
| SCHEMBL12726948 | 0.83 | TLR7 (0.57) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726706 | 0.82 | TLR7 (0.65) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726751 | 0.81 | TLR7 (0.56) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726805 | 0.81 | TLR7 (0.56) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726716 | 0.81 | TLR7 (0.64) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726731 | 0.81 | TLR7 (0.64) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL15695425 | 0.80 | TLR7 (0.62) | TLR7CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507507-B2 | Modulators of toll-like receptors | GILEAD SCIENCES, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20110098248-A1 | MODULATORS OF TOLL-LIKE RECEPTORS | GILEAD SCIENCES, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098248-A1 | MODULATORS OF TOLL-LIKE RECEPTORS | TLR3, TLR6, TLR1 | TLR7 9/4885CYP3A4 4822/4885CYP2D6 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.