Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.44 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747857 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL762630 | 0.97 | MEN1 (0.50) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL745996 | 0.96 | MEN1 (0.51) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL750679 | 0.96 | MEN1 (0.51) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL748618 | 0.94 | CACNA1G (0.42) | CYP3A4CACNA1GCACNA1HCACNA1ICLPP | |
| SCHEMBL748966 | 0.93 | KMT2A (0.47) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL750582 | 0.93 | KMT2A (0.47) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL750742 | 0.91 | MEN1 (0.45) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL750062 | 0.90 | CLPP (0.40) | MEN1KMT2ACYP3A4CACNA1GCACNA1H | |
| SCHEMBL14039074 | 0.90 | CYP3A4 (0.46) | MEN1KMT2ACYP3A4CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932384-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-04-26 | — | — | US | disclosed |
| US-7932384-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-04-26 | — | — | US | disclosed |