SCHEMBL1272854

SCHEMBL1272854

Nc1ncnc2c1ncn2OC=O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 5/20 0.51
▸ ADORA1 P30542 3/20 0.51
▸ PI4KA P42356 4/20 0.47
▸ PI4K2B Q8TCG2 4/20 0.47
▸ PI4K2A Q9BTU6 4/20 0.47
▸ PI4KB Q9UBF8 4/20 0.47
▸ ADORA2B P29275 1/20 0.47
▸ AHCY P23526 5/20 0.47
▸ GSK3B P49841 1/20 0.45
▸ EGFR P00533 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887808 0.79 ADORA2A (0.59) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL385843 0.79 ADORA2A (0.55) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL2698569 0.78 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL16485904 0.78 GSK3B (0.48) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL5663802 0.76 ADORA2A (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL283730 0.76 FGFR1 (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28296105 0.76 ADORA2A (0.47) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL14125909 0.76 ADORA2A (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL27592464 0.75 KDM4E (0.55) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL29254213 0.74 ADORA2A (0.48) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370665-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR ENHANCED DNA TRANSFORMATION IN BACTERIA North Carolina State University (US) 2024-05-22 — — EP disclosed
US-20240117413-A1 SEQUENCING BY EMERGENCE XGENOMES CORP (US) 2024-04-11 — — US disclosed
CN-117441014-A Enzyme composition having at least two different thermostable polypeptides having type II DNA methyltransferase activity 布鲁克生物科技公司 2024-01-23 — — CN disclosed
CN-117441014-A Enzyme composition having at least two different thermostable polypeptides having type II DNA methyltransferase activity 布鲁克生物科技公司 2024-01-23 — — CN disclosed
CN-116426627-A M based on MTR mRNA 6 Method for evaluating repeated spontaneous abortion risk through A methylation modification and application thereof 河南省人民医院 2023-07-14 — — CN disclosed
WO-2023122744-A1 METHYLTRANSFERASE APPLICATION FOR EVALUATING THE METHYLATION STATUS OF A POLYNUCLEOTIDE APR BIOSCIENCES INC. (US) 2023-06-29 — — WO disclosed
WO-2023288250-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR ENHANCED DNA TRANSFORMATION IN BACTERIA NORTH CAROLINA STATE UNIVERSITY (US) 2023-01-19 — — WO disclosed
US-20220359040-A1 SYSTEMS AND METHODS FOR DETERMINING SEQUENCE XGENOMES CORP. 2022-11-10 — — US disclosed
CN-112730554-B Electrode, preparation of biosensor containing electrode and application of electrode in detection of methyltransferase 山东师范大学 2022-09-09 — — CN disclosed
EP-4010473-A1 COMPOSITIONS AND METHODS FOR DETECTING METHYLATED DNA Battelle Memorial Institute (US) 2022-06-15 — — EP disclosed
US-5208157-A Cloning the TaqI restriction and modification genes NEW ENGLAND BIOLABS, INC. (US) 1993-05-04 — — US disclosed
US-5198354-A Genetic engineering NEW ENGLAND BIOLABS, INC. (US) 1993-03-30 — — US disclosed
US-5196331-A Genetic engineering NEW ENGLAND BIOLABS, INC. (US) 1993-03-23 — — US disclosed
US-5196332-A HAE-Haemophilus aegyptius NEW ENGLAND BIOLABS, INC. (US) 1993-03-23 — — US disclosed
US-5180673-A Cloning restriction and modification genes NEW ENGLAND BIOLABS, INC. (US) 1993-01-19 — — US disclosed
US-5137823-A METHOD FOR PRODUCING THE BAMHI RESTRICTION ENDONUCLEASE AND METHYLASE NEW ENGLAND BIOLABS, INC. (US) 1992-08-11 — — US disclosed
EP-0428572-A1 PRODUCING COMMERCIALLY VALUABLE POLYPEPTIDES WITH GENETICALLY TRANSFORMED ENDOSPERM TISSUE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE (US) 1991-05-29 — — EP disclosed
WO-1990001551-A1 PRODUCING COMMERCIALLY VALUABLE POLYPEPTIDES WITH GENETICALLY TRANSFORMED ENDOSPERM TISSUE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE (US) 1990-02-22 — — WO disclosed
EP-0248678-A2 Method for cloning restriction modification system NEW ENGLAND BIOLABS, INC. (US) 1987-12-09 — — EP disclosed
EP-0193413-A2 Cloning restriction and modification genes NEW ENGLAND BIOLABS, INC. (US) 1986-09-03 — — EP disclosed
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