SCHEMBL385843

SCHEMBL385843

Nc1ncnc2c1ncn2OO

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 10/20 0.55
▸ ADORA1 P30542 7/20 0.55
▸ PI4KA P42356 7/20 0.50
▸ PI4K2B Q8TCG2 7/20 0.50
▸ PI4K2A Q9BTU6 7/20 0.50
▸ PI4KB Q9UBF8 7/20 0.50
▸ ADORA2B P29275 2/20 0.50
▸ GSK3B P49841 1/20 0.47
▸ EGFR P00533 1/20 0.47
▸ AHCY P23526 5/20 0.46
▸ ADORA3 P0DMS8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1272854 0.79 ADORA2A (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL14125909 0.78 ADORA2A (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL283730 0.78 FGFR1 (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9275563 0.78 ADORA2A (0.49) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28296105 0.78 ADORA2A (0.47) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28113155 0.77 GSK3B (0.51) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL16485904 0.77 GSK3B (0.48) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28406876 0.77 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL27818519 0.76 ADORA2A (0.50) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9458754 0.75 PI4KA (0.56) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150231177-A1 Methods and Compositions for Controlled and Sustained Production and Delivery of Peroxides and/or Oxygen for Biological and Industrial Applications VIRGINIA COMMONWEALTH UNIVERSITY (US) 2015-08-20 — — US claimed
US-20120207793-A1 Methods and Compositions for Controlled and Sustained Production and Delivery of Peroxides and/or Oxygen for Biological and Industrial Applications VIRGINIA COMMONWEALTH UNIVERSITY 2012-08-16 — — US claimed
EP-2252333-A2 GAS BASED WOUND AND TISSUE THERAPEUTICS Oxygen Biotherapeutics, Inc. (US) 2010-11-24 — — EP claimed
WO-2009102487-A2 GAS BASED WOUND AND TISSUE THERAPEUTICS OXYGEN BIOTHERAPEUTICS, INC. (US) 2009-08-20 — — WO claimed
US-20090169630-A1 Methods and Compositions for Controlled and Sustained Production and Delivery of Peroxides and/or Oxygen for Biological and Industrial Applications VIRGINIA COMMONWEALTH UNIVERSITY 2009-07-02 — — US claimed
EP-2024287-A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES Virginia Commonwealth University (US) 2009-02-18 — — EP claimed
WO-2007134304-A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES VIRGINIA COMMONWEALTH UNIVERSITY (US) 2007-11-22 — — WO claimed
US-20150231177-A1 Methods and Compositions for Controlled and Sustained Production and Delivery of Peroxides and/or Oxygen for Biological and Industrial Applications VIRGINIA COMMONWEALTH UNIVERSITY (US) 2015-08-20 — — US disclosed
US-20130289471-A1 GAS BASED WOUND AND TISSUE THERAPEUTICS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2013-10-31 — — US disclosed
US-20120207793-A1 Methods and Compositions for Controlled and Sustained Production and Delivery of Peroxides and/or Oxygen for Biological and Industrial Applications VIRGINIA COMMONWEALTH UNIVERSITY 2012-08-16 — — US disclosed
US-20120184898-A1 GAS BASED WOUND AND TISSUE THERAPEUTICS TENAX THERAPEUTICS, INC 2012-07-19 — — US disclosed
US-8101117-B2 Controlled gas pore formers in extruded ware CORNING, INCORPORATED (US) 2012-01-24 — — US disclosed
EP-2252333-A2 GAS BASED WOUND AND TISSUE THERAPEUTICS Oxygen Biotherapeutics, Inc. (US) 2010-11-24 — — EP disclosed
US-20090298667-A1 Controlled Gas Pore Formers in Extruded Ware CORNING INCORPORATED 2009-12-03 — — US disclosed
WO-2009102487-A2 GAS BASED WOUND AND TISSUE THERAPEUTICS OXYGEN BIOTHERAPEUTICS, INC. (US) 2009-08-20 — — WO disclosed
US-20090202617-A1 Gas based wound and tissue therapeutics TENAX THERAPEUTICS, INC 2009-08-13 — — US disclosed
US-20090169630-A1 Methods and Compositions for Controlled and Sustained Production and Delivery of Peroxides and/or Oxygen for Biological and Industrial Applications VIRGINIA COMMONWEALTH UNIVERSITY 2009-07-02 — — US disclosed
EP-2024287-A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES Virginia Commonwealth University (US) 2009-02-18 — — EP disclosed
WO-2009006586-A2 SELF-CONTAINED OXYGEN GENERATING AND BREATHING SYSTEMS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2009-01-08 — — WO disclosed
WO-2007134304-A1 METHODS AND COMPOSITIONS FOR CONTROLLED AND SUSTAINED PRODUCTION AND DELIVERY OF PEROXIDES VIRGINIA COMMONWEALTH UNIVERSITY (US) 2007-11-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090202617-A1 Gas based wound and tissue therapeutics PGF, FGF2, FGF1 ADORA2A 2174/4885ADORA1 2826/4885PI4KA 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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