SCHEMBL14125909

SCHEMBL14125909

CC(=O)On1cnc2c(N)ncnc21

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 6/20 0.51
ADORA1 P30542 6/20 0.51
GSK3B P49841 1/20 0.49
AHCY P23526 4/20 0.48
PI4KA P42356 6/20 0.47
PI4K2B Q8TCG2 6/20 0.47
PI4K2A Q9BTU6 6/20 0.47
PI4KB Q9UBF8 6/20 0.47
ADORA2B P29275 2/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
THPO P40225 1/20 0.46
BLM P54132 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.46
EGFR P00533 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28406876 0.98 ADORA2A (0.50) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL16485904 0.83 GSK3B (0.48) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL28113155 0.83 GSK3B (0.51) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL28406873 0.81 ADORA2A (0.50) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL28145519 0.81 ADORA2A (0.50) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL22458325 0.81 FGFR1 (0.45) GSK3BTDP1ALDH1A1
SCHEMBL28086747 0.81 ADORA2A (0.48) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL15297006 0.80 ADCY5 (0.47) ADORA2AADORA1GSK3BAHCYPI4KA
Acetone SCHEMBL28162073 0.80 CYP3A4 (0.47) ADORA2AADORA1GSK3BAHCYPI4KA
SCHEMBL385843 0.78 ADORA2A (0.55) ADORA2AADORA1GSK3BAHCYPI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039583-B Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2025-03-11 CN claimed
CN-119039583-A Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2024-11-29 CN claimed
CN-119039583-B Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2025-03-11 CN disclosed
CN-119039583-A Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2024-11-29 CN disclosed
US-10093674-B2 Supramolecular nanofibers and hydrogels based on nucleic acids functionalized with nucleobases BRANDEIS UNIVERSITY (US) 2018-10-09 US disclosed
US-20180100036-A1 CLICK NUCLEIC ACID POLYMERS AND METHODS OF USE UNIV COLORADO REGENTS (US) 2018-04-12 US disclosed
US-20140148410-A1 Supramolecular Nanofibers and Hydrogels Based on Nucleic Acids Functionalized with Nucleobases BRANDEIS UNIVERSITY (US) 2014-05-29 US disclosed
CN-103145714-A Feather weight PNA (pentose nucleic acid) synthesis method SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD 2013-06-12 CN disclosed
WO-2012166706-A2 SUPRAMOLECULAR NANOFIBERS AND HYDROGELS BASED ON OLIGOPEPTIDES FUNCTIONALIZED WITH NUCLEOBASES BRANDEIS UNIVERSITY (US) 2012-12-06 WO disclosed
WO-2012166705-A2 SUPRAMOLECULAR NANOFIBERS AND HYDROGELS BASED ON AMINO ACID-NUCLEOBASE-GLYCOSIDE CONJUGATES BRANDEIS UNIVERSITY (US) 2012-12-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140148410-A1 Supramolecular Nanofibers and Hydrogels Based on Nucleic Acids Functionalized with Nucleobases PHAX, PCNA, RBM28 ADORA2A 1717/4885ADORA1 2410/4885GSK3B 2931/4885
US-10093674-B2 Supramolecular nanofibers and hydrogels based on nucleic acids functionalized with nucleobases PHAX, PCNA, RBM28 ADORA2A 1717/4885ADORA1 2410/4885GSK3B 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.